LbrM.20.5150

1,2-Dihydroxy-3-keto-5-methylthiopentene dioxygenase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102069 OG7: OG7_0005923 57 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 57 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.26.0130 ⚠
adenine phosphoribosyltransferase
— Both
LbrM.26.0120 ⚠
adenine phosphoribosyltransferase
— OG7
LbrM.34.0360 ⚠
serine palmitoyltransferase, putative
— OG7
LbrM.30.3520 ⚠
casein kinase 1 isoform 2, putative
— OG7
LbrM.15.0150 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LbrM.27.1580 ⚠
Snf7, putative
— OG7
LbrM.34.0990 ⚠
casein kinase I, putative
— OG7
LbrM.15.0140 ⚠
zinc finger (CCCH type) protein, putative
— OG7
LbrM.34.1030 ⚠
zinc finger CCCH domain containing protein 11
— OG7
LbrM.30.3600 ⚠
Zinc finger CCCH domain-containing protein
— OG7
LbrM.27.1900 ⚠
casein kinase I-like protein
— OG7
LbrM.25.2430 ⚠
casein kinase I, putative
— OG7
LbrM.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LbrM.32.2490 ⚠
heat shock protein Hsp20, putative
— OG7
LbrM.20.3330 ⚠
serine palmitoyltransferase-like protein
— OG7
LbrM.04.1230 ⚠
casein kinase I, putative
— OG7
LbrM.32.2870 ⚠
superoxide dismutase, putative
— OG7
LbrM.32.2000 ⚠
iron superoxide dismutase, putative
— OG7
LbrM.08.0330 ⚠
iron superoxide dismutase A, mitochondrial
— OG7
LbrM.32.2860 ⚠
superoxide dismutase, putative
— OG7
LbrM.32.2010 ⚠
iron superoxide dismutase, putative
— OG7
LbrM.12.0810 ⚠
NADH:flavin oxidoreductase/NADH oxidase, puta
— OG7
LbrM.34.1400 ⚠
arginase
— OG7
LbrM.12.0820 ⚠
n-ethylmaleimide reductase-like protein
— OG7
LbrM.12.0030 ⚠
PITH domain-containing protein
— OG7
LbrM.25.1710 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LbrM.25.1700 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LbrM.32.0130 ⚠
N-myristoyl transferase, putative
— OG7
LbrM.23.0400 ⚠
NADP-dependent alcohol dehydrogenase, putativ
— OG7
LbrM.32.1000 ⚠
Alpha/beta hydrolase family, putative
— Both
LbrM.30.2260 ⚠
hypothetical protein, conserved
— Both
LbrM.26.1020 ⚠
hypothetical protein, conserved
— Both
LbrM.20.1280 ⚠
PTP1-interacting protein, 39 kDa, putative
— Both
LbrM.35.3890 ⚠
NUDIX hydrolase 3, putative
— Both
LbrM.35.4410 ⚠
hypothetical protein, conserved
— Both
LbrM.30.2560 ⚠
RNA-binding protein, putative
— OG6
LbrM.23.1820 ⚠
Nucleoside 2-deoxyribosyltransferase, putativ
— Both
LbrM.24.0510 ⚠
hypothetical protein, conserved
— Both
LbrM.35.2380 ⚠
hypothetical protein, conserved
— Both
LbrM.35.6470 ⚠
hypothetical protein, conserved
— Both
LbrM.20.0630 ⚠
Uncharacterized conserved protein (DUF2039),
— Both
LbrM.34.1000 ⚠
casein kinase, putative
— Both
LbrM.31.1640 ⚠
hypothetical protein, conserved
— Both
LbrM.20.2600 ⚠
protein kinase, putative
— OG7
LbrM.35.3670 ⚠
Charged multivesicular body protein 3, putati
— Both
LbrM.32.3790 ⚠
hypothetical protein, conserved
— Both
LbrM.34.1010 ⚠
hypothetical protein, unknown function
— Both
LbrM.33.3230 ⚠
hypothetical protein, conserved
— Both
LbrM.35.6380 ⚠
disgorgin, putative
— Both
LbrM.10.0910 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.