LbrM.29.2740

3',5'-cyclic nucleotide phosphodiesterase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_158139 OG7: OG7_0000695 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.14.0130 ⚠
inosine-guanine nucleoside hydrolase, putativ
— OG7
LbrM.29.0910 ⚠
guanine deaminase, putative
— OG7
LbrM.31.0160 ⚠
paraflagellar rod protein 1D
— OG7
LbrM.27.1990 ⚠
paraflagellar rod protein 5, putative
— OG7
LbrM.29.1830 ⚠
paraflagellar rod protein 1D, putative
— OG7
LbrM.15.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.29.0670 ⚠
flagellar radial spoke protein-like, putative
— OG7
LbrM.13.0250 ⚠
Flagellar radial spoke protein 4/6
— OG7
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
LbrM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— OG7
LbrM.09.0550 ⚠
leucine-rich repeat protein, putative
— OG7
LbrM.18.1610 ⚠
nonspecific nucleoside hydrolase
— OG7
LbrM.29.2410 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LbrM.15.1480 ⚠
cAMP specific phosphodiesterase, putative
— OG7
LbrM.17.1080 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LbrM.18.1190 ⚠
cAMP phosphodiesterase A, putative
— OG7
LbrM.15.1250 ⚠
cAMP specific phosphodiesterase, putative
— OG7
LbrM.25.1540 ⚠
hypothetical protein, conserved
— OG7
LbrM.13.0970 ⚠
adenylosuccinate synthetase, putative
— OG7
LbrM.20.0520 ⚠
nuclear cap binding complex subunit CBP110, p
— OG7
LbrM.24.0920 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LbrM.10.0900 ⚠
hypothetical protein, conserved
— OG7
LbrM.03.0880 ⚠
MORN repeat, putative
— OG7
LbrM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LbrM.28.2580 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LbrM.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LbrM.05.0320 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LbrM.28.0920 ⚠
DNA replication licensing factor MCM2, putati
— OG7
LbrM.24.1840 ⚠
inhibitor of cysteine peptidase
— OG7
LbrM.33.2980 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LbrM.34.4870 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LbrM.32.1250 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LbrM.32.3220 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LbrM.34.0010 ⚠
pyruvate kinase
— OG7
LbrM.34.0070 ⚠
pyruvate kinase, putative (fragment)
— OG7
LbrM.34.0060 ⚠
pyruvate kinase
— OG7
LbrM.34.0040 ⚠
pyruvate kinase
— OG7
LbrM.24.0020 ⚠
clathrin coat assembly protein, putative
— OG7
LbrM.16.1490 ⚠
paraflagellar rod protein 2C
— OG7
LbrM.16.1480 ⚠
paraflagellar rod protein 2C
— OG7
LbrM.12.0220 ⚠
hypothetical protein, unknown function
— OG7
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.