LbrM.13.0250

Flagellar radial spoke protein 4/6
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_137016 OG7: OG7_0007639 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.03.0880 ⚠
MORN repeat, putative
— Both
LbrM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— Both
LbrM.15.0170 ⚠
serine/threonine-protein kinase, putative, pr
— OG7
LbrM.35.6491 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.1760 ⚠
Galactose oxidase, central domain containing
— OG7
LbrM.09.1230 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.4500 ⚠
serine/threonine kinase, putative
— OG7
LbrM.15.0090 ⚠
ATP-dependent protease ATPase subunit HslU1,
— OG7
LbrM.34.1770 ⚠
protein kinase-like protein
— OG7
LbrM.14.1060 ⚠
protein kinase, putative
— OG7
LbrM.24.2170 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.29.2410 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LbrM.33.2090 ⚠
dual-specificity protein kinase, putative
— OG7
LbrM.22.0930 ⚠
hypothetical protein, conserved
— OG7
LbrM.28.2350 ⚠
hypothetical protein, conserved
— OG7
LbrM.27.1990 ⚠
paraflagellar rod protein 5, putative
— OG7
LbrM.24.0490 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LbrM.16.0090 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LbrM.30.3280 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LbrM.17.1080 ⚠
3'5'-cyclic nucleotide phosphodiesterase, put
— OG7
LbrM.20.4400 ⚠
kelch domain-containing protein
— OG7
LbrM.09.1220 ⚠
hypothetical protein, conserved
— OG7
LbrM.18.1190 ⚠
cAMP phosphodiesterase A, putative
— OG7
LbrM.29.2740 ⚠
3',5'-cyclic nucleotide phosphodiesterase, pu
— OG7
LbrM.29.1830 ⚠
paraflagellar rod protein 1D, putative
— OG7
LbrM.35.1610 ⚠
kelch motif containing protein, putative
— OG7
LbrM.35.3400 ⚠
receptor-type adenylate cyclase a-like protei
— OG7
LbrM.20.0970 ⚠
myosin IB heavy chain, putative
— OG7
LbrM.20.5520 ⚠
calpain-like cysteine peptidase, putative, ca
— OG7
LbrM.14.0800 ⚠
protein kinase, putative
— OG7
LbrM.17.0120 ⚠
receptor-type adenylate cyclase b
— Both
LbrM.31.0160 ⚠
paraflagellar rod protein 1D
— Both
LbrM.16.1490 ⚠
paraflagellar rod protein 2C
— Both
LbrM.16.1480 ⚠
paraflagellar rod protein 2C
— Both
LbrM.26.2300 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— Both
LbrM.32.4110 ⚠
myosin XXI, putative
— Both
LbrM.21.1940 ⚠
protein kinase, putative
— Both
LbrM.25.1540 ⚠
hypothetical protein, conserved
— Both
LbrM.17.0110 ⚠
receptor-type adenylate cyclase, putative (fr
— Both
LbrM.32.1250 ⚠
Aminoacyl-tRNA editing domain containing prot
— Both
LbrM.08.0880
stress-induced protein sti1
— OG6
LbrM.20.5380 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.19.1320 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LbrM.09.0230 ⚠
ATP-dependent protease ATPase subunit HslU2
— Both
LbrM.04.0490 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LbrM.24.0020 ⚠
clathrin coat assembly protein, putative
— OG7
LbrM.33.3220 ⚠
Present in the outer mitochondrial membrane p
— Both
LbrM.30.3050
kinesin, putative
— OG6
LbrM.20.5390 ⚠
calpain-like cysteine peptidase, putative, cy
— OG6
LbrM.20.5340 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.