LbrM.28.0920

DNA replication licensing factor MCM2, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101336 OG7: OG7_0001163 110 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 110 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.24.0920 ⚠
DNA replication licensing factor MCM5, putati
— +18 more Both
LbrM.28.2580 ⚠
DNA replication licensing factor MCM6, putati
— +19 more Both
LbrM.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— +17 more OG7
LbrM.05.0320 ⚠
DNA replication licensing factor MCM8, putati
— +17 more OG7
LbrM.34.4870 ⚠
DNA replication licensing factor MCM9, putati
— +17 more OG7
LbrM.33.2980 ⚠
DNA replication licensing factor MCM3, putati
— +18 more Both
LbrM.32.3220 ⚠
DNA replication licensing factor MCM7, putati
— +19 more Both
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.18.1190 ⚠
cAMP phosphodiesterase A, putative
— OG7
LbrM.29.2740 ⚠
3',5'-cyclic nucleotide phosphodiesterase, pu
— OG7
LbrM.15.1250 ⚠
cAMP specific phosphodiesterase, putative
— OG7
LbrM.20.4090 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LbrM.31.0270 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LbrM.17.0950 ⚠
formin, putative
— OG7
LbrM.35.4440 ⚠
GINS complex protein, putative
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.06.0510 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.11.0790 ⚠
adaptin-related protein-like protein
— OG7
LbrM.31.2290 ⚠
ubiquitin-fusion protein
— OG7
LbrM.31.2110 ⚠
ubiquitin-fusion protein
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.14.1440 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.31.2130 ⚠
ubiquitin-fusion protein
— OG7
LbrM.18.0390 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LbrM.35.7120 ⚠
beta adaptin, putative
— OG7
LbrM.31.0230 ⚠
dihydrolipoamide dehydrogenase
— OG7
LbrM.24.1720 ⚠
SpoU rRNA Methylase family, putative
— OG7
LbrM.16.1260 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.04.0600 ⚠
TPR repeat/Tetratricopeptide repeat, putative
— OG7
LbrM.31.1890 ⚠
GINS complex subunit Psf3, putative
— OG7
LbrM.26.0140 ⚠
Mini-chromosome maintenance complex-binding p
— +1 more OG7
LbrM.15.1510 ⚠
hypothetical protein, conserved
— OG7
LbrM.11.1050 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.0330 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LbrM.35.1910 ⚠
hypothetical protein, conserved
— OG7
LbrM.31.2950 ⚠
RNA polymerase ii largest subunit
— OG7
LbrM.33.3060 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LbrM.23.1810 ⚠
neutral sphingomyelinase activation associate
— OG7
LbrM.28.2310 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LbrM.35.2620 ⚠
Cullin protein neddylation domain containing
— OG7
LbrM.35.3280 ⚠
cullin-like protein
— OG7
LbrM.35.0720 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LbrM.11.0080 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LbrM.30.2230 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.32.3180 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LbrM.34.4880 ⚠
tubulin tyrosine ligase, putative
— OG7
LbrM.09.0640 ⚠
ubiquitin-fusion protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.