LbrM.04.0600

TPR repeat/Tetratricopeptide repeat, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_102882 OG7: OG7_0007593 144 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 144 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.03.0280 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LbrM.29.1050
kinesin, putative
— OG6
LbrM.14.1200
hypothetical protein, conserved
— Both
LbrM.29.2710
hypothetical protein, conserved
— Both
LbrM.27.2690
hypothetical protein, conserved, WD-repeat pr
— Both
LbrM.29.1260
hypothetical protein, conserved
— Both
LbrM.26.1140 ⚠
axonemal dynein light chain, putative
— Both
LbrM.32.0320
hypothetical protein, conserved
— Both
LbrM.30.2160
endosomal trafficking protein RME-8, putative
— Both
LbrM.26.1870
microtubule-associated protein, putative
— Both
LbrM.08.0960
intraflagellar transport protein 122B, putati
— Both
LbrM.08.0460
hypothetical protein, conserved
— Both
LbrM.30.0740
pdz domain containing protein, putative
— Both
LbrM.17.0410
hypothetical protein, conserved
— Both
LbrM.16.0770 ⚠
N-terminal region of Chorein, a TM vesicle-me
— Both
LbrM.09.0880
kinetoplast-associated protein-like protein
— OG6
LbrM.35.1580
N-terminal region of Chorein, a TM vesicle-me
— Both
LbrM.35.3290 ⚠
fibrillarin
— Both
LbrM.35.2840
protein kinase, putative
— Both
LbrM.28.2580 ⚠
DNA replication licensing factor MCM6, putati
— Both
LbrM.03.0880 ⚠
MORN repeat, putative
— Both
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— Both
LbrM.11.1050
hypothetical protein, conserved
— Both
LbrM.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.26.0760 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.20.1520 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LbrM.20.5370 ⚠
dynein arm light chain, putative
— OG7
LbrM.29.1160 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.17.1260 ⚠
5'-3' exoribonuclease B, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.35.2810 ⚠
cyclin-e binding protein 1-like protein
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.20.2060 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LbrM.20.3010 ⚠
cleavage and polyadenylation specificity fact
— OG7
LbrM.16.1170 ⚠
WW domain containing protein, putative
— OG7
LbrM.20.5460 ⚠
Raptor N-terminal CASPase like domain contain
— OG7
LbrM.13.1230 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LbrM.35.4300 ⚠
regulator of chromosome condensation 1-like p
— OG7
LbrM.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LbrM.27.1310 ⚠
translation initiation factor eIF2B delta sub
— OG7
LbrM.09.1040 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LbrM.24.0920 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LbrM.33.2980 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LbrM.34.4870 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LbrM.28.0920 ⚠
DNA replication licensing factor MCM2, putati
— OG7
LbrM.32.3220 ⚠
DNA replication licensing factor MCM7, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.