LbrM.17.1260

5'-3' exoribonuclease B, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_156818 OG7: OG7_0003221 192 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 192 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.1630 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LbrM.35.1010 ⚠
eukaryotic translation initiation factor 6 (e
— OG7
LbrM.21.0070 ⚠
hypothetical protein, conserved
— OG7
LbrM.19.1750 ⚠
eukaryotic translation initiation factor-like
— OG7
LbrM.28.1480 ⚠
hypothetical protein, conserved
— OG7
LbrM.32.0130 ⚠
N-myristoyl transferase, putative
— OG7
LbrM.18.0030 ⚠
mevalonate-diphosphate decarboxylase, putativ
— OG7
LbrM.32.1000 ⚠
Alpha/beta hydrolase family, putative
— OG7
LbrM.29.2080 ⚠
Present in the outer mitochondrial membrane p
— OG7
LbrM.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LbrM.31.3170 ⚠
KH domain/Domain of unknown function (DUF1771
— OG7
LbrM.35.3810 ⚠
Protein of unknown function (DUF2009), putati
— OG7
LbrM.32.2280 ⚠
cytidylyltransferase, putative
— OG7
LbrM.30.0530 ⚠
Eukaryotic translation initiation factor 4E-4
— OG7
LbrM.35.7010 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— OG7
LbrM.16.1550 ⚠
hypothetical protein, conserved
— OG7
LbrM.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.16.1390 ⚠
hypothetical protein, conserved
— OG7
LbrM.35.6640 ⚠
ubiquitin-protein ligase, putative
— OG7
LbrM.20.4470 ⚠
Midasin, putative
— OG7
LbrM.20.5370 ⚠
dynein arm light chain, putative
— OG7
LbrM.25.1400 ⚠
General negative regulator of transcription s
— OG7
LbrM.20.1950 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.05.0410 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LbrM.15.1140 ⚠
protein kinase, putative
— OG7
LbrM.14.0770 ⚠
hypothetical protein, conserved
— OG7
LbrM.07.0120 ⚠
Sec7 domain containing protein, putative
— OG7
LbrM.34.5330 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.19.1290 ⚠
WD domain, G-beta repeat, putative
— OG7
LbrM.09.1270 ⚠
AAA family ATPase, putative
— OG7
LbrM.03.0280 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LbrM.21.1570 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LbrM.19.1200 ⚠
CAP-Gly domain containing protein, putative
— OG7
LbrM.03.0980 ⚠
hypothetical protein
— OG7
LbrM.23.1010 ⚠
hypothetical protein, conserved
— OG7
LbrM.14.0900 ⚠
immunodominant antigen, putative, tc40 antige
— OG7
LbrM.11.0630 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0060 ⚠
MATH domain containing protein, putative
— OG7
LbrM.33.1750 ⚠
hypothetical protein, conserved
— OG7
LbrM.30.0570 ⚠
hypothetical protein, conserved
— OG7
LbrM.20.2060 ⚠
Guanine nucleotide exchange factor in Golgi t
— OG7
LbrM.21.0890 ⚠
CCR4-NOT transcription complex subunit 1
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.