LbrM.23.0840

3-ketoacyl-CoA thiolase, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_101329 OG7: OG7_0003757 29 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 29 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.26.0130 ⚠
adenine phosphoribosyltransferase
— Both
LbrM.26.0120 ⚠
adenine phosphoribosyltransferase
— OG7
LbrM.06.0520 ⚠
U-box domain containing protein, putative
— OG7
LbrM.12.0930 ⚠
puromycin-sensitive aminopeptidase-like prote
— OG7
LbrM.26.0330 ⚠
metallo-peptidase, Clan MA(E), Family M1
— OG7
LbrM.20.4800 ⚠
cytidine triphosphate synthase, putative, CTP
— Both
LbrM.34.3250 ⚠
6-phosphogluconate dehydrogenase, decarboxyla
— Both
LbrM.24.2190 ⚠
3-hydroxy-3-methylglutaryl-CoA synthase, puta
— Both
LbrM.32.3200 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.32.3210 ⚠
nucleoside diphosphate kinase b
— Both
LbrM.17.0230 ⚠
cystathionine beta-synthase (fragment)
— Both
LbrM.35.3820 ⚠
cysteine synthase
— OG6
LbrM.05.0800 ⚠
methylthioadenosine phosphorylase, putative
— Both
LbrM.28.0960 ⚠
ribonucleoside-diphosphate reductase large ch
— Both
LbrM.29.2220 ⚠
Aminopeptidase M1, putative
— Both
LbrM.10.0310 ⚠
isocitrate dehydrogenase [NADP], mitochondria
— Both
LbrM.29.0800 ⚠
U-box domain protein, putative
— Both
LbrM.19.0460
mitogen-activated protein kinase kinase kinas
— OG6
LbrM.20.1910 ⚠
Aminotransferase class IV, putative
— Both
LbrM.12.0490 ⚠
glucose-6-phosphate isomerase
— Both
LbrM.26.0840 ⚠
aspartate--ammonia ligase, putative, asparagi
— Both
LbrM.35.3170 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— Both
LbrM.16.0560 ⚠
aspartate carbamoyltransferase, putative
— Both
LbrM.18.0570 ⚠
aconitase, putative
— Both
LbrM.14.1320 ⚠
enolase
— Both
LbrM.14.1330 ⚠
enolase
— Both
LbrM.25.1700 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LbrM.25.1710 ⚠
succinyl-CoA synthetase alpha subunit, putati
— Both
LbrM.30.1370 ⚠
pyridoxal kinase, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.