LbrM.31.1080

protein phosphatase 2C, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_158272 OG7: OG7_0000783 42 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 42 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.08.0010
adaptor complex protein (AP) 3 delta subunit
— OG6
LbrM.20.2350
hypothetical protein, conserved
— OG6
LbrM.20.1390
Nucleoporin NUP225
— OG6
LbrM.21.1450
adenylate kinase, putative
— OG6
LbrM.30.1230
RNA-binding protein, putative
— OG6
LbrM.05.1110 ⚠
DNA-directed RNA polymerase I largest subunit
— OG6
LbrM.16.1400 ⚠
DNA-directed rna polymerase I largest subunit
— OG6
LbrM.17.0940 ⚠
ATP-dependent RNA helicase, putative
— OG6
LbrM.13.0320 ⚠
ATP-dependent RNA helicase, putative
— OG6
LbrM.25.1240
Cullin family/Cullin protein neddylation doma
— OG6
LbrM.23.0610
hypothetical protein, conserved
— OG6
LbrM.34.2430
hypothetical protein, conserved
— OG6
LbrM.29.1870
hypothetical protein, conserved
— OG6
LbrM.18.0910
hypothetical protein, conserved
— OG6
LbrM.14.0550
WD domain, G-beta repeat, putative
— OG6
LbrM.15.0710
hypothetical protein, conserved
— OG6
LbrM.27.0890
parallel beta-helix repeat, putative
— OG6
LbrM.08.0540
ribose-phosphate pyrophosphokinase, putative
— OG6
LbrM.16.0720
ubiquitin hydrolase, putative, cysteine pepti
— OG6
LbrM.31.1440
Protein of unknown function (DUF3638)/Protein
— OG6
LbrM.23.0130
Concanavalin A-like lectin/glucanases superfa
— OG6
LbrM.18.0920
Periodic tryptophan protein 2 homolog, putati
— OG6
LbrM.04.0170
exosome complex exonuclease RRP40, putative
— OG6
LbrM.03.0430
hypothetical protein, conserved
— OG6
LbrM.25.2130
RNA polymerase I second largest subunit, puta
— OG6
LbrM.30.0260
cysteine peptidase, Clan CA, family C19, puta
— OG6
LbrM.25.0290
RNA-binding protein, putative
— OG6
LbrM.26.1100
hypothetical protein, conserved
— OG6
LbrM.30.2390
hypothetical protein, conserved
— OG6
LbrM.26.1440
FYVE zinc finger, putative
— OG6
LbrM.28.1620
Cell division control protein 48, putative
— OG6
LbrM.30.3750
CPSF-domain protein, putative
— OG6
LbrM.20.4950
protein kinase, putative
— OG6
LbrM.05.0860
CPSF A subunit region, putative
— OG6
LbrM.35.5490
glycosyl hydrolase, putative
— OG6
LbrM.35.3160
phosphatidylinositol 3- and 4-kinase, putativ
— OG6
LbrM.31.3340
acetyl-CoA carboxylase
— OG6
LbrM.35.5510
Adaptor protein complex AP-3 subunit beta-3
— OG6
LbrM.32.2890
SpoU rRNA Methylase family, putative
— OG6
LbrM.33.1310
hypothetical protein, conserved
— OG6
LbrM.20.1740
Glycosyl hydrolase family 65 central catalyti
— OG6
LbrM.32.0810
hypothetical protein, conserved
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.