LbrM.04.0680

hypothetical protein, conserved (fragment)
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_146432 OG7: OG7_0042903 46 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 46 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.20.2670 ⚠
phosphatidylinositol phosphate kinase alpha
— OG7
LbrM.34.4690 ⚠
glycine cleavage system H protein, putative
— Both
LbrM.08.0480 ⚠
hypothetical protein, conserved
— Both
LbrM.29.1480 ⚠
LYAR-type C2HC zinc finger, putative
— Both
LbrM.04.0550 ⚠
Nucleotidyltransferase domain containing prot
— Both
LbrM.26.0510 ⚠
DNA polymerase sigma-like protein
— OG7
LbrM.07.0770 ⚠
topoisomerase-related function protein-like p
— OG7
LbrM.35.3160 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LbrM.35.6620 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LbrM.32.4210 ⚠
cAMP response protein 1, putative
— OG7
LbrM.02.0130 ⚠
phosphatidylinositol kinase related protein,
— OG7
LbrM.03.0370 ⚠
MFS transporter, putative
— OG7
LbrM.20.3550 ⚠
target of rapamycin kinase 3, putative
— Both
LbrM.19.0620 ⚠
RNA binding protein
— OG7
LbrM.20.5280 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LbrM.20.3990 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LbrM.13.0150 ⚠
protein kinase A regulatory subunit
— OG7
LbrM.20.5730 ⚠
Myotubularin-related protein, putative
— OG7
LbrM.17.1580 ⚠
major facilitator superfamily, putative
— OG7
LbrM.21.0120 ⚠
major facilitator superfamily, putative
— OG7
LbrM.20.2440 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LbrM.32.1620 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LbrM.35.0460 ⚠
phosphatidylinositol-4-phosphate 5-kinase-lik
— OG7
LbrM.29.1470 ⚠
LYAR-type C2HC zinc finger, putative
— Both
LbrM.26.1020 ⚠
hypothetical protein, conserved
— Both
LbrM.26.1320 ⚠
Nucleolar protein 105, putative
— Both
LbrM.20.4730 ⚠
hypothetical protein, conserved
— Both
LbrM.19.0610 ⚠
RNA binding protein, putative
— Both
LbrM.15.1140 ⚠
protein kinase, putative
— Both
LbrM.34.3380 ⚠
acyl transferase-like protein, putative
— Both
LbrM.20.3720 ⚠
GRIP domain containing protein, putative
— Both
LbrM.06.0340 ⚠
hypothetical protein, conserved
— Both
LbrM.20.4580 ⚠
major facilitator superfamily, putative
— Both
LbrM.20.1680 ⚠
hypothetical protein, conserved
— Both
LbrM.14.1390 ⚠
hypothetical protein, conserved
— Both
LbrM.35.5980 ⚠
hypothetical protein, conserved
— Both
LbrM.29.2400 ⚠
hypothetical protein, unknown function
— Both
LbrM.21.0670 ⚠
RNA helicase, putative
— Both
LbrM.32.3090 ⚠
CS domain/TPR repeat/Tetratricopeptide repeat
— Both
LbrM.34.0560 ⚠
phosphatidylinositol-4-phosphate 5-kinase-lik
— Both
LbrM.34.2190 ⚠
hypothetical protein, conserved
— Both
LbrM.29.2690 ⚠
Lipase (class 3), putative
— Both
LbrM.26.0740 ⚠
hypothetical protein, conserved
— Both
LbrM.31.1560 ⚠
hypothetical protein, conserved
— Both
LbrM.13.0910 ⚠
hypothetical protein, conserved
— Both
LbrM.12.0350 ⚠
Myotubularin-related protein, putative
— Both
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.