LbrM.21.0870

ras-related protein Rab21, putative
Leishmania braziliensis MHOM/BR/75/M2904 OG6: OG6_103363 OG7: OG7_0000131 19 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 19 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LbrM.32.2020
rab11B GTPase, putative
— OG6
LbrM.18.0190 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LbrM.07.0190
protein phosphatase 2A, regulatory subunit B,
— OG6
LbrM.30.3070
homoserine kinase
— OG6
LbrM.01.0140
monothiol glutaredoxin, putative
— OG6
LbrM.09.1300
hypothetical protein, conserved
— OG6
LbrM.04.0570
palmitoyl acyltransferase 1, putative
— OG6
LbrM.02.0420
ubiquitin-conjugating enzyme E2, putative
— OG6
LbrM.17.0340
cytidine deaminase-like protein
— OG6
LbrM.22.1160
hypothetical protein, unknown function
— OG6
LbrM.31.2910
hypothetical protein, unknown function
— OG6
LbrM.29.1500 ⚠
RNA binding protein, putative
— OG6
LbrM.20.1190
Uncharacterised ACR, YggU family COG1872, put
— OG6
LbrM.32.3790
hypothetical protein, conserved
— OG6
LbrM.35.6800
hypothetical protein, unknown function
— OG6
LbrM.35.1350
hypothetical protein, conserved
— OG6
LbrM.29.1510 ⚠
RNA binding protein, putative
— OG6
LbrM.18.0200 ⚠
RNA recognition motif. (a.k.a. RRM, RBD, or R
— OG6
LbrM.26.2030
protein kinase, putative
— OG6
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.