LmjF.04.0550

TPR repeat/Tetratricopeptide repeat, putative
Leishmania major strain Friedlin OG6: OG6_102882 OG7: OG7_0007593 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.19.0680 ⚠
Flagellum attachment zone protein 7
— OG6
LmjF.30.2210
endosomal trafficking protein RME-8, putative
— Both
LmjF.27.2170 ⚠
hypothetical protein, conserved
— Both
LmjF.34.1510
hypothetical protein, conserved
— Both
LmjF.35.4010 ⚠
cAMP-dependent protein kinase catalytic subun
— OG6
LmjF.21.0800
CCR4-NOT transcription complex subunit 1
— Both
LmjF.09.0800
kinetoplast-associated protein-like protein
— OG6
LmjF.32.1470 ⚠
Microtubule-binding protein MIP-T3, putative
— Both
LmjF.22.1500
ATP-dependent DEAD/H RNA helicase, putative
— OG6
LmjF.29.2250
hypothetical protein, conserved
— Both
LmjF.24.1970
Nucleoporin NUP76
— Both
LmjF.25.0200
Putative intraflagellar transport protein F6
— Both
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— Both
LmjF.16.0780 ⚠
N-terminal region of Chorein, a TM vesicle-me
— Both
LmjF.11.0830
hypothetical protein, conserved
— Both
LmjF.05.0190
Fip1 motif/Zinc finger C-x8-C-x5-C-x3-H type
— Both
LmjF.28.2385 ⚠
DNA replication licensing factor MCM6, putati
— Both
LmjF.03.0970 ⚠
MORN repeat, putative
— Both
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— Both
LmjF.11.1300
hypothetical protein, conserved
— Both
LmjF.05.1080 ⚠
Phosphatidylinositol 4-phosphate 5-kinase, pu
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.16.1550 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.1470 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.33.3060 ⚠
46 kD virulence factor
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.34.1390 ⚠
N-terminal region of Chorein, a TM vesicle-me
— OG7
LmjF.27.1210 ⚠
translation initiation factor eIF2B delta sub
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.24.0840 ⚠
dynein arm light chain, putative
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.10.0950 ⚠
translation initiation factor eIF-2B subunit
— OG7
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.21.1566 ⚠
Microtubule-binding protein MIP-T3, putative
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.08.0010 ⚠
adaptor complex protein (AP) 3 delta subunit
— OG7
LmjF.05.0330 ⚠
DNA replication licensing factor MCM8, putati
— OG7
LmjF.33.2700 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LmjF.32.2960 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LmjF.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.