LmjF.08.0010

adaptor complex protein (AP) 3 delta subunit 1, putative
Leishmania major strain Friedlin OG6: OG6_101525 OG7: OG7_0001761 208 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 208 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.30.0660 ⚠
pdz domain containing protein, putative
— OG7
LmjF.04.0960 ⚠
UMP/CMP kinase, putative
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmjF.32.0250 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.30.0710 ⚠
CDC16, putative
— OG7
LmjF.36.1000 ⚠
intraflagellar transport protein 122, putativ
— OG7
LmjF.19.1010 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.28.2760 ⚠
gamma-tubulin complex component 3
— OG7
LmjF.23.0900 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.0840 ⚠
dynein arm light chain, putative
— OG7
LmjF.33.1490 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LmjF.30.0050 ⚠
MATH domain containing protein, putative
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.31.3110 ⚠
Flagellum attachment zone protein 14
— OG7
LmjF.29.1180 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.0380 ⚠
Nuclear pore complex protein 158
— OG7
LmjF.21.1670 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.3060 ⚠
cullin-like protein
— OG7
LmjF.26.1120 ⚠
axonemal dynein light chain, putative
— OG7
LmjF.14.0790 ⚠
hypothetical protein, conserved
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— +2 more OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— +2 more OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— +2 more OG7
LmjF.11.0830 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2480 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.2620 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.5020 ⚠
hypothetical protein, conserved
— OG7
LmjF.02.0700 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0320 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0790 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.0260 ⚠
Midasin, putative
— OG7
LmjF.03.0270 ⚠
FYVE zinc finger/Apolipoprotein A1/A4/E domai
— OG7
LmjF.21.1330 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.23.0020 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.3060 ⚠
46 kD virulence factor
— OG7
LmjF.16.1550 ⚠
hypothetical protein, conserved
— OG7
LmjF.13.1470 ⚠
SPRY domain/HECT-domain (ubiquitin-transferas
— OG7
LmjF.05.0400 ⚠
structural maintenance of chromosome (SMC), p
— OG7
LmjF.36.1790 ⚠
5'-3' exoribonuclease D, putative
— OG7
LmjF.12.0110 ⚠
hypothetical protein, conserved
— OG7
LmjF.06.0260 ⚠
5'-3' exoribonuclease A, putative
— OG7
LmjF.21.0530 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.