LmjF.06.0260

5'-3' exoribonuclease A, putative
Leishmania major strain Friedlin OG6: OG6_100417 OG7: OG7_0003221 206 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 206 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.31.1070 ⚠
biotin/lipoate protein ligase-like protein
— Both
LmjF.32.3660 ⚠
3-hydroxyisobutyryl-coenzyme a hydrolase-like
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.34.3970 ⚠
AP-1 adapter complex gamma subunit, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.31.2880 ⚠
aldehyde reductase, putative
— OG7
LmjF.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmjF.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmjF.23.1480 ⚠
alanine racemase, putative
— Both
LmjF.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmjF.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— Both
LmjF.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LmjF.04.0690 ⚠
axonemal dynein light chain, putative
— Both
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— Both
LmjF.25.1290 ⚠
NPL4 family, putative
— Both
LmjF.25.2010 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LmjF.18.0990 ⚠
UDP-glucose pyrophosphorylase
— Both
LmjF.30.0180 ⚠
2-hydroxy-3-oxopropionate reductase, putative
— Both
LmjF.32.2400 ⚠
hypothetical protein, conserved
— Both
LmjF.29.2100 ⚠
Present in the outer mitochondrial membrane p
— Both
LmjF.12.0020 ⚠
PITH domain-containing protein
— Both
LmjF.35.0030 ⚠
pyruvate kinase
— Both
LmjF.35.4470 ⚠
Co-chaperone protein P23
— Both
LmjF.30.2610 ⚠
RNA-binding protein, putative
— OG6
LmjF.26.1910 ⚠
deoxyhypusine hydroxylase, putative
— Both
LmjF.31.2810 ⚠
KH domain/Domain of unknown function (DUF1771
— Both
LmjF.36.0890 ⚠
eukaryotic translation initiation factor 6 (e
— Both
LmjF.36.6250 ⚠
small G-protein, putative
— OG6
LmjF.20.0600 ⚠
hypothetical protein, conserved
— Both
LmjF.36.6650 ⚠
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.33.0090 ⚠
hypothetical protein, conserved
— Both
LmjF.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LmjF.31.0570 ⚠
amino acid transporter aATP11, putative
— OG6
LmjF.32.0910 ⚠
Alpha/beta hydrolase family, putative
— Both
LmjF.18.0210 ⚠
Activator of Hsp90 ATPase, N-terminal/Activat
— Both
LmjF.34.2000 ⚠
pyroglutamyl-peptidase I (C15 family)
— Both
LmjF.16.0580 ⚠
dihydroorotase, putative
— Both
LmjF.21.0150 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
Page 1 of 5
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.