LmjF.29.2100

Present in the outer mitochondrial membrane proteome 37
Leishmania major strain Friedlin OG6: OG6_105186 OG7: OG7_0009787 189 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 189 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.1380 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.10.0200 ⚠
Mitogen-activated protein kinase 10, putative
— OG6
LmjF.33.0090 ⚠
hypothetical protein, conserved
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— Both
LmjF.31.1070 ⚠
biotin/lipoate protein ligase-like protein
— Both
LmjF.25.2010 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— Both
LmjF.25.1290 ⚠
NPL4 family, putative
— Both
LmjF.27.0490 ⚠
calpain-like cysteine peptidase, putative
— Both
LmjF.26.1210 ⚠
aldo/keto reductase, putative
— Both
LmjF.24.0640 ⚠
Kinesin-13 3, putative
— Both
LmjF.30.0660 ⚠
pdz domain containing protein, putative
— Both
LmjF.16.1340 ⚠
hypothetical protein, conserved
— Both
LmjF.31.0570 ⚠
amino acid transporter aATP11, putative
— OG6
LmjF.26.0320 ⚠
C-1-tetrahydrofolate synthase, cytoplasmic, p
— Both
LmjF.30.2600 ⚠
formate--tetrahydrofolate ligase
— OG6
LmjF.13.0140 ⚠
hypothetical protein, conserved
— Both
LmjF.22.0110 ⚠
GMP synthase [glutamine-hydrolysing]
— Both
LmjF.16.0760 ⚠
transaldolase, putative
— Both
LmjF.06.0260 ⚠
5'-3' exoribonuclease A, putative
— Both
LmjF.36.1790 ⚠
5'-3' exoribonuclease D, putative
— Both
LmjF.31.1560 ⚠
hypothetical protein, conserved
— Both
LmjF.22.1470 ⚠
hypothetical protein, conserved
— Both
LmjF.23.1240 ⚠
hypothetical protein, conserved
— Both
LmjF.16.0010 ⚠
hypothetical protein, conserved
— Both
LmjF.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— Both
LmjF.24.0370 ⚠
aspartate aminotransferase, putative
— Both
LmjF.35.0820 ⚠
aspartate aminotransferase, putative
— Both
LmjF.26.0270 ⚠
ras-like small GTPases, putative
— Both
LmjF.28.1110 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.28.1140 ⚠
electron-transfer-flavoprotein, alpha polypep
— Both
LmjF.23.1480 ⚠
alanine racemase, putative
— Both
LmjF.22.0320 ⚠
SEP domain containing protein, putative
— Both
LmjF.31.0140 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— Both
LmjF.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— Both
LmjF.11.1370 ⚠
tRNA pseudouridine synthase D (TruD), putativ
— Both
LmjF.33.2810 ⚠
transcription elongation factor-like protein
— Both
LmjF.31.0290 ⚠
Kinesin-13 4, putative
— OG7
LmjF.13.1610 ⚠
Kinesin-13 5, putative
— OG7
LmjF.01.0030 ⚠
Kinesin-13 1, putative
— OG7
LmjF.13.0130 ⚠
Kinesin-13 2
— OG7
LmjF.08.0870 ⚠
hypothetical protein, unknown function
— OG7
LmjF.27.2410 ⚠
aldo-keto reductase-like protein
— OG7
LmjF.31.2880 ⚠
aldehyde reductase, putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.28.1340 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.28.1350 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.28.1360 ⚠
haloacid dehalogenase-like hydrolase-like pro
— OG7
LmjF.29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmjF.34.0150 ⚠
malate dehydrogenase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.