LmjF.28.1380

haloacid dehalogenase-like hydrolase-like protein
Leishmania major strain Friedlin OG6: OG6_152033 OG7: OG7_0005628 168 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 168 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.12.0020 ⚠
PITH domain-containing protein
— OG7
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— OG7
LmjF.28.2070 ⚠
tRNA threonylcarbamoyl adenosine modification
— OG7
LmjF.28.1960 ⚠
Elongation factor G 2, mitochondrial, putativ
— OG7
LmjF.31.1070 ⚠
biotin/lipoate protein ligase-like protein
— OG7
LmjF.25.2010 ⚠
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldola
— OG7
LmjF.25.1290 ⚠
NPL4 family, putative
— OG7
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG7
LmjF.07.0050 ⚠
alpha-adaptin-like protein
— OG7
LmjF.36.2950 ⚠
succinyl-CoA ligase [GDP-forming] beta-chain,
— OG7
LmjF.32.2450 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmjF.32.2070 ⚠
phosphopantetheine adenylyltransferase, putat
— OG7
LmjF.33.0730 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.36.1470 ⚠
kelch motif containing protein, putative
— OG7
LmjF.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmjF.29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmjF.07.0900 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.25.1020 ⚠
dehydrogenase-like protein
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.24.0480 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.25.2140 ⚠
succinyl-CoA synthetase alpha subunit, putati
— OG7
LmjF.28.2000 ⚠
protein lipid droplet kinase (LDK)
— OG7
LmjF.32.0080 ⚠
N-myristoyl transferase, putative
— OG7
LmjF.03.0570 ⚠
quinone oxidoreductase, putative
— OG7
LmjF.31.1610 ⚠
diphthine synthase-like protein
— OG7
LmjF.01.0210 ⚠
CUE domain/Domain of unknown function (DUF177
— OG7
LmjF.34.3780 ⚠
phosphomannomutase-like protein
— OG7
LmjF.32.0960 ⚠
ubiquitin-conjugating enzyme protein, putativ
— OG7
LmjF.33.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.0810 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
LmjF.29.0780 ⚠
U-box domain protein, putative
— OG7
LmjF.13.0730 ⚠
ubiquitin-like protein
— OG7
LmjF.32.3680 ⚠
3-hydroxyisobutyryl-coenzyme A hydrolase, put
— OG7
LmjF.34.0210 ⚠
CS domain containing protein, putative
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.20.0210 ⚠
kelch domain-containing protein
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.29.0340 ⚠
UBX domain-containing protein
— OG7
LmjF.32.1580 ⚠
phosphomannose isomerase
— OG7
LmjF.03.0760 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6170 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.2090 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.31.2510 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.31.0255 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.2480 ⚠
ferredoxin 2fe-2s-like protein
— OG7
LmjF.36.6180 ⚠
Sucrase/ferredoxin-like, putative
— OG7
LmjF.26.1050 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.