LmjF.35.2410

ubiquitin hydrolase, putative
Leishmania major strain Friedlin OG6: OG6_136424 OG7: OG7_0001214 210 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 210 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.18.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.0547 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.4090 ⚠
GRIP domain containing protein, putative
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.36.3960 ⚠
hypothetical protein, unknown function
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.36.1360 ⚠
adenylate kinase, putative
— OG7
LmjF.33.1110 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.32.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmjF.29.0140 ⚠
DNA-directed RNA polymerase II subunit 3, put
— OG7
LmjF.31.2510 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LmjF.32.1870 ⚠
Cation efflux family, putative
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.34.3460 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1050 ⚠
2Fe-2S iron-sulfur cluster binding domain con
— OG7
LmjF.31.2500 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LmjF.36.3160 ⚠
tubulin binding cofactor c, putative
— OG7
LmjF.25.0220 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.1370 ⚠
haloacid dehalogenase-like hydrolase, putativ
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.31.2490 ⚠
ferredoxin, 2fe-2s-like protein
— OG7
LmjF.31.2970 ⚠
acetyl-CoA carboxylase
— OG7
LmjF.10.1200 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LmjF.10.0130 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LmjF.27.1340 ⚠
hypothetical protein, unknown function
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.36.3090 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0600 ⚠
arginine N-methyltransferase, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.32.1680 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.22.1230 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.1020 ⚠
hypothetical protein, conserved
— OG7
LmjF.06.0540 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.1260 ⚠
mitochondrial DNA polymerase I protein A, put
— OG7
LmjF.20.1060 ⚠
hypothetical protein, unknown function
— OG7
LmjF.06.0830 ⚠
lipin, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.