LmjF.18.0820

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_102176 OG7: OG7_0007065 170 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 170 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— +2 more Both
LmjF.31.1210
Protein of unknown function (DUF3638)/Protein
— +2 more Both
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.34.2240
Glycosyl hydrolase family 65 central catalyti
— +2 more Both
LmjF.23.0547
hypothetical protein, conserved
— +2 more Both
LmjF.36.5240
glycosyl hydrolase, putative
— +2 more Both
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— +1 more Both
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.03.0970 ⚠
MORN repeat, putative
— OG7
LmjF.33.1930 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.08.1130 ⚠
phosphoribosylpyrophosphate synthetase
— OG7
LmjF.36.5390 ⚠
phosphoribosylpyrophosphate synthetase, putat
— OG7
LmjF.13.0080 ⚠
mitochondrial DNA polymerase I protein B, put
— OG7
LmjF.30.3470 ⚠
casein kinase 1 isoform 2, putative
— OG7
LmjF.04.1210 ⚠
casein kinase I, putative
— OG7
LmjF.35.1000 ⚠
casein kinase I, putative
— OG7
LmjF.34.3020 ⚠
CK1/TTBK protein kinase, putative
— OG7
LmjF.25.1580 ⚠
casein kinase I, putative
— OG7
LmjF.27.1780 ⚠
casein kinase I-like protein
— OG7
LmjF.13.1350 ⚠
AAA domain/Dpy-30 motif containing protein, p
— OG7
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmjF.32.1400 ⚠
ATP-dependent DNA DEAD/DEAH box helicase, put
— OG7
LmjF.23.1380 ⚠
DNA polymerase theta (helicase domain only),
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.12.0300
hypothetical protein, conserved
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.30.2540 ⚠
AAA family ATPase-like protein
— OG7
LmjF.27.1050 ⚠
vesicular transport protein (CDC48 homologue)
— OG7
LmjF.20.1530 ⚠
cell division cycle protein-like protein
— OG7
LmjF.27.0360 ⚠
ATPase, putative
— OG7
LmjF.34.3520 ⚠
peroxisome biosynthesis protein-like protein
— OG7
LmjF.16.0060 ⚠
peroxisome assembly protein, putative
— OG7
LmjF.11.0910 ⚠
Bromodomain factor 7, putative
— OG7
LmjF.14.0960 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LmjF.34.1000 ⚠
myosin IB heavy chain, putative
— OG7
LmjF.26.0390 ⚠
RET2, RNA editing complex MP57
— OG7
LmjF.28.0780 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.36.3060 ⚠
cullin-like protein
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.32.1360 ⚠
RNA capping enzyme, cytoplasmic
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.33.2780 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.