LmjF.35.1740

ubiquitin hydrolase, putative
Leishmania major strain Friedlin OG6: OG6_101317 OG7: OG7_0002166 229 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 229 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.04.0030 ⚠
cAMP-specific phosphodiesterase, putative
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— OG7
LmjF.36.5590 ⚠
adenylyl cyclase-associated protein, putative
— OG7
LmjF.14.0960 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LmjF.09.0940 ⚠
translation-associated element 2, putative
— OG7
LmjF.34.2750 ⚠
methyltransferase-like protein
— OG7
LmjF.28.0890 ⚠
ribonucleoside-diphosphate reductase large ch
— OG7
LmjF.32.1680 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
LmjF.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— OG7
LmjF.34.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.08.0910 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmjF.14.1360 ⚠
inositol-3-phosphate synthase
— OG7
LmjF.09.1180 ⚠
hypothetical protein, conserved
— OG7
LmjF.09.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.0560 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.1820 ⚠
Replication factor A protein 1
— OG7
LmjF.30.3420 ⚠
T-complex protein 11, putative
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.35.3260 ⚠
Peroxin 19
— OG7
LmjF.18.1450 ⚠
Protein of unknown function (DUF3648), putati
— OG7
LmjF.19.0100 ⚠
fibrillarin, putative
— OG7
LmjF.34.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LmjF.21.1130 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.0750 ⚠
proteasome activator protein pa26, putative
— OG7
LmjF.17.0430 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.2450 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.33.2910 ⚠
hypothetical protein, conserved
— OG7
LmjF.21.0910 ⚠
Aminoacyl-tRNA editing domain containing prot
— OG7
LmjF.25.1315 ⚠
DNA-directed RNA polymerase I subunit RPB10,
— OG7
LmjF.24.0620 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.28.0230 ⚠
hypothetical protein, unknown function
— OG7
LmjF.33.0550 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.20.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1880 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.2730 ⚠
Stabilization of polarity axis, putative
— OG7
LmjF.36.6140 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.2460 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0020 ⚠
nuclear segregation protein, putative
— OG7
LmjF.36.4370 ⚠
ubiquitin protein ligase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.