LmjF.36.4370

ubiquitin protein ligase, putative
Leishmania major strain Friedlin OG6: OG6_478893 OG7: OG7_0002947 158 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 158 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.34.4540 ⚠
13 kDa deflagellation-inducible protein, puta
— OG7
LmjF.23.0310 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.2130 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.25.1705 ⚠
LSM domain containing protein, putative
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LmjF.26.0005 ⚠
Lsm7p protein, putative
— OG7
LmjF.35.4460 ⚠
sm-f snRNP core complex protein, putative
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.32.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmjF.30.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG7
LmjF.05.0610 ⚠
Surp module, putative
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.28.1820 ⚠
Replication factor A protein 1
— OG7
LmjF.28.2010 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.0550 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.1220 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.1010 ⚠
glutamate dehydrogenase
— OG7
LmjF.34.2750 ⚠
methyltransferase-like protein
— OG7
LmjF.21.0875 ⚠
hypothetical protein, conserved
— OG7
LmjF.09.1210 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.18.1570 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.10.1140 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.18.1150 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.30.3360 ⚠
calmodulin-related protein, putative
— OG7
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LmjF.05.0230 ⚠
hydrogenase, putative
— OG7
LmjF.30.1550 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LmjF.23.0320 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.0780 ⚠
Tubulin/FtsZ family, putative
— OG7
LmjF.30.0520 ⚠
N-acetyltransferase B complex (NatB) non cata
— OG7
LmjF.32.1040 ⚠
hypothetical protein, conserved
— OG7
LmjF.09.1100 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.0630 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.20.0940 ⚠
cyclophilin 15, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.