LmjF.08.0410

WD domain, G-beta repeat, putative
Leishmania major strain Friedlin OG6: OG6_107301 OG7: OG7_0010331 195 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 195 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.24.2020
tubulin folding cofactor D, putative
— Both
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.18.0550
hypothetical protein, conserved
— Both
LmjF.33.1910
ribosome assembly protein RRB1, putative
— Both
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmjF.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmjF.19.1040
phenylalanyl-tRNA synthetase, putative
— Both
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.30.0560
hypothetical protein, conserved
— Both
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— Both
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.0920
hypothetical protein, conserved
— Both
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.10.0160
hypothetical protein, conserved
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.36.4920
hypothetical protein, conserved
— Both
LmjF.15.1210 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LmjF.35.4230 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LmjF.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.34.1220 ⚠
inositol 5-phosphatase-like protein
— OG7
LmjF.07.0760 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmjF.03.0800 ⚠
6-phosphofructo-2-kinase 1
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.34.2760
hypothetical protein, conserved
— Both
LmjF.25.2300
Leucine Rich repeats (2 copies), putative
— Both
LmjF.32.0210
Histone chaperone Rttp106-like, putative
— Both
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmjF.23.0490
5'-AMP-activated protein kinase subunit beta,
— Both
LmjF.36.3090
hypothetical protein, conserved
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.09.0740
ubiquitin ligase, putative
— Both
LmjF.23.0110
GDP-mannose pyrophosphorylase
— Both
LmjF.26.1900 ⚠
hypothetical protein, conserved
— Both
LmjF.10.1200 ⚠
hypothetical protein, conserved
— Both
LmjF.02.0310
Soluble NSF attachment protein, SNAP, putativ
— Both
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.36.4230
paraflagellar rod component, putative
— OG6
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.