LmjF.18.0550

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_147460 OG7: OG7_0043380 154 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 154 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.22.0650
guide RNA associated protein, GAP2, putative
— Both
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— Both
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— Both
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— Both
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— Both
LmjF.08.0410
WD domain, G-beta repeat, putative
— Both
LmjF.33.1910
ribosome assembly protein RRB1, putative
— Both
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— Both
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— Both
LmjF.18.1320
hypothetical protein, conserved
— Both
LmjF.15.0180 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.31.1370
hypothetical protein, conserved
— OG7
LmjF.06.0940 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1955 ⚠
TLD, putative
— OG7
LmjF.22.0590
Uncharacterised protein family UPF0066, putat
— Both
LmjF.11.0920
Short C-terminal domain/PUB domain containing
— Both
LmjF.01.0610
DNA-damage inducible protein DDI1-like protei
— Both
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— Both
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0890
hypothetical protein, conserved
— Both
LmjF.30.1230
Zinc finger, C3HC4 type (RING finger), putati
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.13.0940
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LmjF.24.2020
tubulin folding cofactor D, putative
— Both
LmjF.36.4230
paraflagellar rod component, putative
— OG6
LmjF.18.0070 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— Both
LmjF.05.0850 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.29.0290 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.36.0490 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0085 ⚠
elongation factor 1-alpha
— OG7
LmjF.35.4150 ⚠
elongation factor 1-alpha, putative
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0080 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0086 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0084 ⚠
elongation factor 1-alpha
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.02.0120 ⚠
phosphatidylinositol kinase related protein,
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.20.1120 ⚠
phosphatidylinositol 3-kinase, putative
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.35.1860 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.33.1830 ⚠
dual specificity tyrosine-phosphorylation-reg
— OG7
LmjF.32.1070 ⚠
small nuclear ribonucleoprotein, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.4460 ⚠
sm-f snRNP core complex protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.