LmjF.24.2020

tubulin folding cofactor D, putative
Leishmania major strain Friedlin OG6: OG6_102599 OG7: OG7_0006853 203 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 203 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.08.0410
WD domain, G-beta repeat, putative
— Both
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— +2 more Both
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— +2 more Both
LmjF.19.1040
phenylalanyl-tRNA synthetase, putative
— Both
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.30.0560
hypothetical protein, conserved
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— +1 more Both
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— Both
LmjF.24.1900
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.28.2500 ⚠
Eukaryotic translation initiation factor 4E-3
— OG7
LmjF.36.4890 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1500 ⚠
Eukaryotic translation initiation factor 4E-2
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.27.1340
hypothetical protein, unknown function
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.35.0700
vacuolar ATP synthase subunit d, putative
— Both
LmjF.17.0540 ⚠
ATPase family associated with various cellula
— OG7
LmjF.36.6710 ⚠
replication factor C subunit 3, putative
— OG7
LmjF.20.1090 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.3250 ⚠
replication factor C, subunit 3, putative
— OG7
LmjF.27.0550 ⚠
replication factor C, subunit 4, putative
— OG7
LmjF.30.2630 ⚠
replication factor C, subunit 2, putative
— OG7
LmjF.35.0900
hypothetical protein, conserved
— Both
LmjF.18.0550
hypothetical protein, conserved
— Both
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG6
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.20.1180 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.34.1990
Zeta toxin, putative
— Both
LmjF.28.2820 ⚠
heat shock protein 70, putative
— Both
LmjF.36.6770 ⚠
beta adaptin, putative
— Both
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG6
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG6
LmjF.34.4290
nucleolar protein family a, putative
— Both
LmjF.30.1230
Zinc finger, C3HC4 type (RING finger), putati
— Both
LmjF.21.1340
ATP synthase, putative
— Both
LmjF.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.36.5420
branch point binding protein, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.