LmjF.36.6350

poly(A)-specific ribonuclease PARN, putative
Leishmania major strain Friedlin OG6: OG6_102215 OG7: OG7_0005534 200 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 200 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LmjF.18.1040 ⚠
5-oxoprolinase, putative
— Both
LmjF.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— Both
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— Both
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— +1 more Both
LmjF.29.1780 ⚠
diphthamide synthesis protein, putative
— OG7
LmjF.10.1200 ⚠
hypothetical protein, conserved
— Both
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.21.0340 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.36.1260 ⚠
fructose-1,6-bisphosphate aldolase
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.32.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— Both
LmjF.28.0160 ⚠
RNA binding protein, putative
— OG7
LmjF.20.0790 ⚠
tubulin-tyrosine ligase, putative
— OG7
LmjF.23.0110 ⚠
GDP-mannose pyrophosphorylase
— Both
LmjF.29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmjF.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.34.4030 ⚠
geranylgeranyltransferase, putative
— OG7
LmjF.35.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmjF.11.0380 ⚠
Domain of unknown function(DUF2779), putative
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.35.3370 ⚠
hypothetical protein, conserved
— Both
LmjF.17.1400 ⚠
otubain cysteine peptidase, Clan CA, family C
— Both
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.35.1470 ⚠
choline/ethanolamine kinase, putative
— Both
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— Both
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— Both
LmjF.30.0560 ⚠
hypothetical protein, conserved
— Both
LmjF.09.0740 ⚠
ubiquitin ligase, putative
— Both
LmjF.32.0715 ⚠
U6 snRNA-associated Sm-like protein LSm4p
— Both
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.30.1205 ⚠
small nuclear ribonucleoprotein polypeptide e
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.01.0160 ⚠
LSM domain containing protein, putative
— OG7
LmjF.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.