LmjF.18.0370

tubulin tyrosine ligase protein, putative
Leishmania major strain Friedlin OG6: OG6_104969 OG7: OG7_0001164 146 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 146 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.08.0650 ⚠
DnaJ domain containing protein, putative
— OG7
LmjF.34.0360 ⚠
DNA-directed RNA polymerase III subunit C1, p
— OG7
LmjF.36.2790 ⚠
Flagellar Member 1
— OG7
LmjF.36.3530 ⚠
polyubiquitin, putative
— OG7
LmjF.28.2110 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.16.1220 ⚠
Cullin family/Cullin protein neddylation doma
— OG7
LmjF.32.0140 ⚠
Flagellum attachment zone protein 9
— OG7
LmjF.16.0660 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmjF.24.1660 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.14.1270 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.30.0250 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.22.1120 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmjF.24.2100 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— OG7
LmjF.29.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.0850 ⚠
DNA replication licensing factor MCM2, putati
— OG7
LmjF.22.1130 ⚠
Beta-lactamase superfamily domain containing
— OG7
LmjF.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmjF.31.2610 ⚠
RNA polymerase ii largest subunit
— OG7
LmjF.33.2700 ⚠
DNA replication licensing factor MCM3, putati
— OG7
LmjF.29.1830 ⚠
dihydrolipoamide dehydrogenase, putative
— OG7
LmjF.23.1570 ⚠
neutral sphingomyelinase activation associate
— OG7
LmjF.25.0620 ⚠
RNA polymerase I second largest subunit, puta
— OG7
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.27.0860 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.17.0930 ⚠
formin, putative
— OG7
LmjF.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.32.1460 ⚠
phosphatidylinositol 3-related kinase, putati
— OG7
LmjF.36.4210 ⚠
WD domain, G-beta repeat/Utp21 specific WD40
— OG7
LmjF.32.2650 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.22.1630 ⚠
ccr4-not transcription complex subunit
— OG7
LmjF.25.1490 ⚠
Rab3 GTPase-activating protein catalytic subu
— OG7
LmjF.25.1000 ⚠
hypothetical protein, conserved
— OG7
LmjF.16.1270 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0080 ⚠
DnaJ domain containing protein, putative
— OG7
LmjF.04.0490 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0750 ⚠
TatD related DNase, putative
— OG7
LmjF.11.0260 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0610 ⚠
kinase-like protein
— OG7
LmjF.11.0370 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1260 ⚠
fructose-1,6-bisphosphate aldolase
— OG7
LmjF.13.1240 ⚠
Thiamin pyrophosphokinase, vitamin B1 binding
— OG7
LmjF.01.0140 ⚠
hypothetical protein, conserved
— OG7
LmjF.07.0550 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0470 ⚠
pumillio protein 10, putative
— OG7
LmjF.09.0950 ⚠
O-phosphoseryl-tRNA(Sec) selenium transferase
— OG7
LmjF.28.0160 ⚠
RNA binding protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.