LmjF.07.0550

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_478677 OG7: OG7_0293510 195 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 195 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.2385 ⚠
DNA replication licensing factor MCM6, putati
— OG7
LmjF.24.2100
hypothetical protein, conserved
— Both
LmjF.16.0380 ⚠
tubulin tyrosine ligase, putative
— Both
LmjF.09.0980
hypothetical protein, conserved
— Both
LmjF.08.0110
hypothetical protein, unknown function
— Both
LmjF.15.1010
glutamate dehydrogenase
— Both
LmjF.30.0560
hypothetical protein, conserved
— Both
LmjF.34.3940 ⚠
target of rapamycin kinase 3
— Both
LmjF.10.1080
Eukaryotic translation initiation factor 4 ga
— Both
LmjF.29.1900
hypothetical protein, conserved
— Both
LmjF.28.0850 ⚠
DNA replication licensing factor MCM2, putati
— Both
LmjF.33.2560
Unc104-like kinesin, putative
— OG6
LmjF.34.0300 ⚠
hypothetical protein, conserved
— Both
LmjF.23.0490
5'-AMP-activated protein kinase subunit beta,
— Both
LmjF.09.0940
translation-associated element 2, putative
— Both
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— Both
LmjF.02.0310
Soluble NSF attachment protein, SNAP, putativ
— Both
LmjF.04.0350
hypothetical protein, conserved
— Both
LmjF.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LmjF.06.0190
hypothetical protein, conserved
— Both
LmjF.34.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmjF.36.3000 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.30.1200 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.35.4910 ⚠
DNA replication licensing factor MCM9, putati
— OG7
LmjF.24.0910 ⚠
DNA replication licensing factor MCM5, putati
— OG7
LmjF.36.3060 ⚠
cullin-like protein
— OG7
LmjF.17.0170 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.34.4530 ⚠
Phosphatidylinositol 3-kinase tor2
— OG7
LmjF.36.0600 ⚠
ubiquitin/ribosomal protein S27a, putative
— OG7
LmjF.32.0760 ⚠
cyclin 9, putative
— OG7
LmjF.09.0250 ⚠
DNA replication licensing factor MCM4, putati
— OG7
LmjF.24.2290 ⚠
cullin-like protein-like protein
— OG7
LmjF.21.0400 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.09.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6320 ⚠
Phosphatidylinositol 3-kinase tor1
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.31.2650 ⚠
acetoin dehydrogenase e3 component-like prote
— OG7
LmjF.31.2030 ⚠
ubiquitin-fusion protein
— OG7
LmjF.36.2410 ⚠
Cullin protein neddylation domain containing
— OG7
LmjF.29.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.31.1900 ⚠
ubiquitin-fusion protein
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.06.0500 ⚠
SpoU rRNA Methylase family, putative
— OG7
LmjF.36.2940 ⚠
phosphatidylinositol 3- and 4-kinase, putativ
— OG7
LmjF.32.2960 ⚠
DNA replication licensing factor MCM7, putati
— OG7
LmjF.35.3500 ⚠
zinc finger protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.