LmjF.10.1080

Eukaryotic translation initiation factor 4 gamma 5
Leishmania major strain Friedlin OG6: OG6_139892 OG7: OG7_0037732 102 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 102 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.32.1370
G5-interacting protein, putative
— Both
LmjF.31.1340 ⚠
'Cold-shock' DNA-binding domain containing pr
— OG7
LmjF.04.0030
cAMP-specific phosphodiesterase, putative
— Both
LmjF.21.0930 ⚠
histone H2A, putative
— Both
LmjF.29.1730 ⚠
histone H2A, putative
— Both
LmjF.29.1720 ⚠
histone H2A, putative
— Both
LmjF.21.0920 ⚠
histone H2A, putative
— Both
LmjF.29.1740 ⚠
histone H2A, putative
— Both
LmjF.21.0915 ⚠
histone H2A
— Both
LmjF.28.0825 ⚠
RNA binding protein rbp16, putative
— Both
LmjF.08.0110
hypothetical protein, unknown function
— Both
LmjF.07.0550
hypothetical protein, conserved
— Both
LmjF.02.0460 ⚠
Mitochondrial outer membrane protein porin, p
— Both
LmjF.09.1180 ⚠
hypothetical protein, conserved
— Both
LmjF.09.0980
hypothetical protein, conserved
— Both
LmjF.08.0910
Beta-lactamase superfamily domain containing
— Both
LmjF.23.0050 ⚠
cyclophilin 11, putative
— OG6
LmjF.33.1630 ⚠
cyclophilin 4, putative
— OG6
LmjF.25.0910 ⚠
cyclophilin a, putative
— OG6
LmjF.04.0350
hypothetical protein, conserved
— Both
LmjF.01.0430 ⚠
Ring finger domain/Zn-finger in ubiquitin-hyd
— Both
LmjF.11.0480
mRNA cap guanine-N7 methyltransferase, putati
— Both
LmjF.12.0350
CCR4-NOT transcription complex subunit 2, put
— Both
LmjF.36.6920
Ribosomal protein L1p/L10e family, putative
— Both
LmjF.21.0800
CCR4-NOT transcription complex subunit 1
— Both
LmjF.06.0190
hypothetical protein, conserved
— Both
LmjF.26.0240
Eukaryotic translation initiation factor 4E t
— Both
LmjF.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.19.0630 ⚠
histone H3 variant V
— OG7
LmjF.34.3280 ⚠
Zn-finger in ubiquitin-hydrolases and other p
— OG7
LmjF.35.4750 ⚠
glyceraldehyde-3-phosphate dehydrogenase-like
— OG7
LmjF.09.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1610 ⚠
universal minicircle sequence binding protein
— OG7
LmjF.11.0140 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.35.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— OG7
LmjF.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.32.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.21.0820 ⚠
Temperature dependent protein affecting M2 ds
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.21.0400 ⚠
Peptidase C19, ubiquitin carboxyl-terminal hy
— OG7
LmjF.17.0280 ⚠
histone H2A variant Z
— OG7
LmjF.02.0450 ⚠
voltage-dependent anion-selective channel, pu
— OG7
LmjF.30.1200 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.17.0170 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.32.0760 ⚠
cyclin 9, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.24.0620 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.15.1520
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.