LmjF.27.0860

WD domain, G-beta repeat, putative
Leishmania major strain Friedlin OG6: OG6_200147 OG7: OG7_0063820 71 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 71 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.05.0970
3-mercaptopyruvate sulfurtransferase
— Both
LmjF.32.2930 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— OG7
LmjF.29.0260 ⚠
Tubulin-tyrosine ligase family, putative
— OG7
LmjF.16.0380 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.35.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.08.0310 ⚠
Isochorismatase family, putative
— OG7
LmjF.15.1200 ⚠
STE group serine/threonine-protein kinase, pu
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.33.2610 ⚠
Mitochondrial-processing peptidase subunit al
— OG7
LmjF.21.0340 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— OG7
LmjF.17.0250
cystathionine beta-synthase
— OG7
LmjF.25.2430 ⚠
Xaa-Pro aminopeptidase, putative
— OG7
LmjF.33.2300
udp-glc 4'-epimerase, putative
— OG7
LmjF.36.3910
S-adenosylhomocysteine hydrolase
— OG7
LmjF.07.0805
N-acetylglucosamine-phosphate mutase, putativ
— OG7
LmjF.02.0040 ⚠
Xaa-Pro aminopeptidase, putative
— OG7
LmjF.34.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— OG7
LmjF.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmjF.27.2660 ⚠
peptidyl dipeptidase, putative
— OG7
LmjF.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— OG7
LmjF.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmjF.34.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.35.3060 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmjF.33.2130
hypothetical protein, conserved
— Both
LmjF.31.1890 ⚠
peptidase m20/m25/m40 family-like protein
— Both
LmjF.33.1610 ⚠
cytosolic nonspecific dipeptidase, putative
— Both
LmjF.33.3050
tyrosyl-DNA phosphodiesterase 1
— Both
LmjF.28.2010
hypothetical protein, conserved
— Both
LmjF.30.1980
C2H2 type zinc-finger (2 copies), putative
— Both
LmjF.03.0770
Ubiquitin-like domain containing protein, put
— Both
LmjF.20.0790 ⚠
tubulin-tyrosine ligase, putative
— Both
LmjF.30.3440 ⚠
DNA ligase I, putative
— Both
LmjF.23.0550 ⚠
ubiquitin-activating enzyme E1, putative
— Both
LmjF.15.1170
hypothetical protein, conserved
— Both
LmjF.03.0610
kinase-like protein
— Both
LmjF.07.0100
metallo-peptidase, Clan ME, Family M16C
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.