LmjF.05.0970

3-mercaptopyruvate sulfurtransferase
Leishmania major strain Friedlin OG6: OG6_100692 OG7: OG7_0004631 137 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 137 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.27.0860
WD domain, G-beta repeat, putative
— Both
LmjF.34.3960 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.02.0040 ⚠
Xaa-Pro aminopeptidase, putative
— Both
LmjF.07.0805
N-acetylglucosamine-phosphate mutase, putativ
— Both
LmjF.36.3910
S-adenosylhomocysteine hydrolase
— Both
LmjF.36.2360
tyrosine aminotransferase
— Both
LmjF.14.1160
enolase
— Both
LmjF.35.4470 ⚠
Co-chaperone protein P23
— Both
LmjF.33.1380 ⚠
mitogen-activated protein kinase 11, putative
— OG6
LmjF.36.6650
2,3-bisphosphoglycerate-independent phosphogl
— Both
LmjF.18.1660
gamma-glutamylcysteine synthetase, putative
— Both
LmjF.33.2610 ⚠
Mitochondrial-processing peptidase subunit al
— Both
LmjF.02.0360
casein kinase II, alpha chain, putative
— OG6
LmjF.03.0750
TatD related DNase, putative
— Both
LmjF.05.0230
hydrogenase, putative
— Both
LmjF.21.0340 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.13.0870 ⚠
mitochondrial processing peptidase alpha subu
— OG7
LmjF.27.2490 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.16.0390 ⚠
XRN 5'-3' exonuclease N-terminus, putative
— OG7
LmjF.23.0310 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.26.0750 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.11.0400 ⚠
tubulin-tyrsoine ligase-like protein
— OG7
LmjF.05.0790 ⚠
Mitochondrial glycoprotein, putative
— OG7
LmjF.33.0200 ⚠
metallo-peptidase, Clan MC, Family M14, putat
— OG7
LmjF.10.0570 ⚠
zinc-binding dehydrogenase-like protein
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.32.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LmjF.34.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.09.1210 ⚠
Zinc finger, C3HC4 type (RING finger), putati
— OG7
LmjF.26.2080 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmjF.18.0370 ⚠
tubulin tyrosine ligase protein, putative
— OG7
LmjF.35.4930 ⚠
tubulin tyrosine ligase, putative
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.12.0060 ⚠
ribonuclease mar1
— OG7
LmjF.32.1090 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.31.2720 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.30.2280 ⚠
tubulin-tyrosine ligase-like protein
— OG7
LmjF.08.0300 ⚠
Isochorismatase family, putative
— OG7
LmjF.35.5210 ⚠
GTP-binding protein, putative
— OG7
LmjF.29.2730 ⚠
START domain containing protein, putative
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.15.1200 ⚠
STE group serine/threonine-protein kinase, pu
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.