LmjF.33.2610

Mitochondrial-processing peptidase subunit alpha
Leishmania major strain Friedlin OG6: OG6_102381 OG7: OG7_0001887 84 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 84 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.2030 ⚠
NADH dehydrogenase subunit NB6M, putative
— OG7
LmjF.34.2820 ⚠
regulatory subunit of protein kinase a-like p
— OG7
LmjF.34.3550 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmjF.33.0140 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.30.3260 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.35.5310 ⚠
ribosome-interacting GTPase 2, putative
— OG7
LmjF.35.1380 ⚠
mitochondrial processing peptidase, beta subu
— OG7
LmjF.15.1200 ⚠
STE group serine/threonine-protein kinase, pu
— OG7
LmjF.07.0060 ⚠
cytochrome c1, heme protein, mitochondrial, p
— OG7
LmjF.01.0830 ⚠
metallo-peptidase, Clan MA(E), Family M3
— Both
LmjF.28.0330 ⚠
rrp44p homologue, putative
— Both
LmjF.32.1790 ⚠
hypothetical protein, conserved
— Both
LmjF.36.3590 ⚠
cysteine synthase
— OG6
LmjF.33.1380 ⚠
mitogen-activated protein kinase 11, putative
— OG6
LmjF.25.1730 ⚠
hypothetical protein, conserved
— Both
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— Both
LmjF.34.1400 ⚠
d-isomer specific 2-hydroxyacid dehydrogenase
— Both
LmjF.24.0650 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.22.0810 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
LmjF.32.1330 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmjF.28.2000 ⚠
protein lipid droplet kinase (LDK)
— OG7
LmjF.09.1310 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmjF.07.0900 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.29.2020 ⚠
5'-AMP-activated protein kinase catalytic sub
— OG7
LmjF.09.1300 ⚠
PPPDE putative peptidase domain containing pr
— OG7
LmjF.36.0900 ⚠
SNF1-related protein kinases, putative
— OG7
LmjF.21.0150 ⚠
CAMK/CAMKL pseudokinase, putative
— OG7
LmjF.11.0700 ⚠
anion-transporting ATPase-like protein
— Both
LmjF.18.0640 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LmjF.32.3970 ⚠
cAMP response protein 1, putative
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
LmjF.27.0860 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.36.4450 ⚠
mitochondrial intermediate peptidase, putativ
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.11.0390 ⚠
hypothetical protein, conserved
— Both
LmjF.18.1040 ⚠
5-oxoprolinase, putative
— Both
LmjF.13.0160 ⚠
protein kinase A regulatory subunit
— Both
LmjF.24.0190 ⚠
hypothetical protein, conserved
— Both
LmjF.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— Both
LmjF.35.2300 ⚠
hypothetical protein, conserved
— Both
LmjF.35.3070 ⚠
hypothetical protein, conserved
— Both
LmjF.33.2300 ⚠
udp-glc 4'-epimerase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.