LmjF.28.0450

DIS3-like exonuclease, putative
Leishmania major strain Friedlin OG6: OG6_102526 OG7: OG7_0002439 238 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 238 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.14.1360 ⚠
inositol-3-phosphate synthase
— +1 more Both
LmjF.25.0870 ⚠
Atypical serine/threonine protein kinase BUD3
— +1 more Both
LmjF.20.1560 ⚠
amidohydrolase, putative
— Both
LmjF.20.1570 ⚠
amidohydrolase, putative
— Both
LmjF.35.4550 ⚠
hypothetical protein, conserved
— +1 more Both
LmjF.30.1380 ⚠
amidohydrolase, putative
— Both
LmjF.15.0690 ⚠
hypothetical protein, conserved
— Both
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LmjF.33.1400 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG7
LmjF.20.1550 ⚠
amidohydrolase, putative
— Both
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.14.1170 ⚠
ras-like small GTPases, putative
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.31.1410 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.34.1470 ⚠
EAP30/Vps36 family, putative
— OG7
LmjF.35.2670 ⚠
ankyrin repeat protein, putative
— OG7
LmjF.30.1540 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.36.1400 ⚠
The ARF-like 2 binding protein BART, putative
— OG7
LmjF.18.1330 ⚠
cholinephosphate cytidylyltransferase A, puta
— OG7
LmjF.33.1710 ⚠
CAMK/CAMKL family protein kinase, putative
— OG7
LmjF.18.0220 ⚠
RNA-binding protein 29, putative
— OG7
LmjF.22.0810 ⚠
calcium/calmodulin-dependent protein kinase,
— OG7
LmjF.18.1100 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.18.1040 ⚠
5-oxoprolinase, putative
— OG7
LmjF.19.0980 ⚠
FYVE zinc finger, putative
— OG7
LmjF.26.1260 ⚠
hypothetical protein, unknown function
— OG7
LmjF.07.0100 ⚠
metallo-peptidase, Clan ME, Family M16C
— OG7
LmjF.17.1130 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.03.0480 ⚠
Ankyrin repeats (3 copies)/DHHC palmitoyltran
— OG7
LmjF.21.0950 ⚠
Programmed cell death protein 2, C-terminal p
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.26.1420 ⚠
FYVE zinc finger, putative
— OG7
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.36.2250 ⚠
developmentally regulated GTP-binding protein
— OG7
LmjF.34.4280 ⚠
Ankyrin repeats (3 copies), putative
— OG7
LmjF.36.0470 ⚠
dihydrouridine synthase domain protein-like p
— OG7
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.15.0980 ⚠
DNA repair protein Rad9, putative
— OG7
LmjF.25.1730 ⚠
hypothetical protein, conserved
— OG7
LmjF.04.0520 ⚠
palmitoyl acyltransferase 1, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.