LmjF.25.0870

Atypical serine/threonine protein kinase BUD32, putative
Leishmania major strain Friedlin OG6: OG6_101388 OG7: OG7_0005083 157 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 157 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.4550 ⚠
hypothetical protein, conserved
— Both
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— +1 more Both
LmjF.14.1360 ⚠
inositol-3-phosphate synthase
— Both
LmjF.22.0470 ⚠
Putative tRNA binding domain containing prote
— OG7
LmjF.11.1000 ⚠
pyruvate phosphate dikinase, putative
— OG7
LmjF.35.5210 ⚠
GTP-binding protein, putative
— OG7
LmjF.05.0200 ⚠
50S ribosome-binding GTPase, putative
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
LmjF.33.2400 ⚠
ras-like small GTPases, putative
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LmjF.25.1030 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.16.0310 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.30.1380 ⚠
amidohydrolase, putative
— OG7
LmjF.20.1550 ⚠
amidohydrolase, putative
— OG7
LmjF.20.1560 ⚠
amidohydrolase, putative
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.20.1570 ⚠
amidohydrolase, putative
— OG7
LmjF.36.4100 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.12.0280 ⚠
ornithine decarboxylase, putative
— OG7
LmjF.35.1310 ⚠
histone H4
— OG7
LmjF.25.2450 ⚠
histone H4
— OG7
LmjF.31.3180 ⚠
histone H4
— OG7
LmjF.02.0020 ⚠
histone H4
— OG7
LmjF.36.0020 ⚠
histone H4
— OG7
LmjF.15.0010 ⚠
histone H4
— OG7
LmjF.21.0015 ⚠
histone H4
— OG7
LmjF.06.0010 ⚠
histone H4
— OG7
LmjF.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmjF.30.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.17.1310 ⚠
methyltransferase domain containing protein,
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.35.2950 ⚠
pentatricopeptide repeat domain containing pr
— OG7
LmjF.30.1540 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
LmjF.31.1410 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.0800 ⚠
DNL zinc finger, putative
— OG7
LmjF.31.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.33.0770 ⚠
G1 cyclin CycE4, putative
— OG7
LmjF.17.0940 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
LmjF.24.1880 ⚠
cyclin 11, putative
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.32.0820 ⚠
CYC2-like cyclin, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.