LmjF.20.1550

amidohydrolase, putative

Leishmania major strain Friedlin OG6: OG6_101553 OG7: OG7_0005942 189 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 189 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.33.2570 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_332700.1 OG6 LdBPK_201740.1 ↔ LdBPK_332700.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 +7 more	Both
LmjF.11.0630 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LmjF.11.0620 ⚠ metallo-peptidase, Clan MF, Family M17	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LmjF.28.0330 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_280470.1 OG6 LdBPK_201740.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 +1 more	Both
LmjF.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	Both
LmjF.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_280470.1 OG7 LdBPK_201740.1 ↔ LdBPK_280470.1	OG7
LmjF.36.5620 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG6 LdBPK_201720.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_008414 OG7 LdBPK_201720.1 ↔ LdBPK_365870.1	Both
LmjF.34.0160 ⚠ mitochondrial malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LmjF.26.1370 ⚠ guanine nucleotide-binding protein-like prote	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LmjF.33.2400 ⚠ ras-like small GTPases, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LmjF.05.0460 ⚠ GTPase, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LmjF.35.5210 ⚠ GTP-binding protein, putative	—	OG7 LdBPK_050200.1 ↔ LdBPK_201720.1 OG7 LdBPK_050200.1 ↔ LdBPK_201740.1	OG7
LmjF.14.1370 ⚠ tyrosyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001244 ↔ TCSYLVIO_008414	OG7
LmjF.12.1300 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.06.1000 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.33.0510 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.23.0820 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.27.0160 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.34.1050 ⚠ TPR repeat/SET domain containing protein, put	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.23.0790 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.24.1750 ⚠ SET domain containing protein, putative	—	OG7 LdBPK_080820.1 ↔ LdBPK_201720.1	OG7
LmjF.34.3500 ⚠ ruvb-like 1 DNA helicase, putative	—	OG7 TCSYLVIO_003846 ↔ TCSYLVIO_008414	OG7
LmjF.17.0620 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LmjF.17.0780 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LmjF.34.2600 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_201720.1 OG7 LdBPK_090800.1 ↔ LdBPK_201740.1	OG7
LmjF.29.2060 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_201720.1 OG7 LdBPK_130530.1 ↔ LdBPK_201740.1	OG7
LmjF.33.1120 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_004910 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004910 ↔ TCSYLVIO_008414	Both
LmjF.12.0280 ⚠ ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_201720.1 OG6 LdBPK_120105.1 ↔ LdBPK_201740.1 OG7 LdBPK_120105.1 ↔ LdBPK_201720.1 OG7 LdBPK_120105.1 ↔ LdBPK_201740.1	Both
LmjF.24.1435 ⚠ hypothetical protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_241480.1 OG7 LdBPK_201720.1 ↔ LdBPK_241480.1	Both
LmjF.33.1910 ⚠ ribosome assembly protein RRB1, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_332020.1 OG6 LdBPK_201740.1 ↔ LdBPK_332020.1 OG7 LdBPK_201720.1 ↔ LdBPK_332020.1 OG7 LdBPK_201740.1 ↔ LdBPK_332020.1	Both
LmjF.30.1540 ⚠ phosphopantothenoylcysteine decarboxylase, pu	—	OG6 LdBPK_201720.1 ↔ LdBPK_301550.1 OG6 LdBPK_201740.1 ↔ LdBPK_301550.1 OG7 LdBPK_201720.1 ↔ LdBPK_301550.1 OG7 LdBPK_201740.1 ↔ LdBPK_301550.1	Both
LmjF.35.2270 ⚠ ATP-dependent RNA helicase-like protein	—	OG6 LdBPK_201720.1 ↔ LdBPK_352320.1 OG6 LdBPK_201740.1 ↔ LdBPK_352320.1	OG6
LmjF.27.2050 ⚠ ribonucleoside-diphosphate reductase small ch	—	OG6 LdBPK_201720.1 ↔ LdBPK_221110.1 OG6 LdBPK_201740.1 ↔ LdBPK_221110.1 OG7 LdBPK_201720.1 ↔ LdBPK_221110.1 OG7 LdBPK_201740.1 ↔ LdBPK_221110.1	Both
LmjF.34.1470 ⚠ EAP30/Vps36 family, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_341570.1 OG6 LdBPK_201740.1 ↔ LdBPK_341570.1 OG7 LdBPK_201720.1 ↔ LdBPK_341570.1 OG7 LdBPK_201740.1 ↔ LdBPK_341570.1	Both
LmjF.20.1560 ⚠ amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LmjF.24.1890 ⚠ cyclin 10	—	OG6 LdBPK_201720.1 ↔ LdBPK_241960.1 OG6 LdBPK_201740.1 ↔ LdBPK_241960.1 OG7 LdBPK_201720.1 ↔ LdBPK_241960.1 OG7 LdBPK_201740.1 ↔ LdBPK_241960.1	Both
LmjF.33.2980 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_333140.1 OG6 LdBPK_201740.1 ↔ LdBPK_333140.1 OG7 LdBPK_201720.1 ↔ LdBPK_333140.1 OG7 LdBPK_201740.1 ↔ LdBPK_333140.1	Both
LmjF.20.1570 ⚠ amidohydrolase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_201740.1 OG7 LdBPK_201720.1 ↔ LdBPK_201740.1	Both
LmjF.22.0520 ⚠ Rab-GTPase-TBC domain containing protein, put	—	OG6 LdBPK_201720.1 ↔ LdBPK_220400.1 OG6 LdBPK_201740.1 ↔ LdBPK_220400.1 OG7 LdBPK_201720.1 ↔ LdBPK_220400.1 OG7 LdBPK_201740.1 ↔ LdBPK_220400.1	Both
LmjF.29.2150 ⚠ cdc2-related kinase 10, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_292260.1 OG6 LdBPK_201740.1 ↔ LdBPK_292260.1 OG7 LdBPK_201720.1 ↔ LdBPK_292260.1 OG7 LdBPK_201740.1 ↔ LdBPK_292260.1	Both
LmjF.07.0340 ⚠ ATP-dependent RNA helicase DBP2B, putative	—	OG7 LdBPK_201720.1 ↔ LdBPK_282220.1 OG7 LdBPK_201740.1 ↔ LdBPK_282220.1	OG7
LmjF.34.0140 ⚠ malate dehydrogenase	—	OG6 TCSYLVIO_004390 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_004390 ↔ TCSYLVIO_008414	Both
LmjF.30.0730 ⚠ co-chaperone GrpE, putative	—	OG6 TCSYLVIO_003139 ↔ TCSYLVIO_008414 OG7 TCSYLVIO_003139 ↔ TCSYLVIO_008414	Both
LmjF.24.1100 ⚠ pre-mRNA-splicing factor ATP-dependent RNA he	—	OG6 LdBPK_201720.1 ↔ LdBPK_241120.1 OG6 LdBPK_201740.1 ↔ LdBPK_241120.1	OG6
LmjF.28.2080 ⚠ DEAD-box ATP-dependent RNA helicase, mitochon	—	OG6 LdBPK_201720.1 ↔ LdBPK_282220.1 OG6 LdBPK_201740.1 ↔ LdBPK_282220.1 OG7 LdBPK_201720.1 ↔ LdBPK_282220.1 OG7 LdBPK_201740.1 ↔ LdBPK_282220.1	Both
LmjF.31.1410 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_311440.1 OG6 LdBPK_201740.1 ↔ LdBPK_311440.1 OG7 LdBPK_201720.1 ↔ LdBPK_311440.1 OG7 LdBPK_201740.1 ↔ LdBPK_311440.1	Both
LmjF.35.4550 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_354620.1 OG6 LdBPK_201740.1 ↔ LdBPK_354620.1 OG7 LdBPK_201720.1 ↔ LdBPK_354620.1 OG7 LdBPK_201740.1 ↔ LdBPK_354620.1	Both
LmjF.34.1150 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_201720.1 ↔ LdBPK_341230.1 OG6 LdBPK_201740.1 ↔ LdBPK_341230.1 OG7 LdBPK_201720.1 ↔ LdBPK_341230.1 OG7 LdBPK_201740.1 ↔ LdBPK_341230.1	Both
LmjF.20.0705 ⚠ conserved protein, unknown function	—	OG6 LdBPK_200770.1 ↔ LdBPK_201720.1 OG6 LdBPK_200770.1 ↔ LdBPK_201740.1 OG7 LdBPK_200770.1 ↔ LdBPK_201720.1 OG7 LdBPK_200770.1 ↔ LdBPK_201740.1	Both
LmjF.30.2040 ⚠ calpain-like cysteine peptidase, putative	—	OG6 LdBPK_201720.1 ↔ LdBPK_302040.1 OG6 LdBPK_201740.1 ↔ LdBPK_302040.1	OG6

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