LmjF.11.0630

metallo-peptidase, Clan MF, Family M17

Leishmania major strain Friedlin OG6: OG6_142599 OG7: OG7_0003405 288 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Interactions 288 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.30.1380 ⚠ amidohydrolase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LmjF.20.1550 ⚠ amidohydrolase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LmjF.20.1560 ⚠ amidohydrolase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LmjF.31.1130 ⚠ amidohydrolase, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008414 OG7 LdBPK_110630.1 ↔ LdBPK_201720.1 OG7 LdBPK_110640.1 ↔ LdBPK_201720.1 OG7 LdBPK_110630.1 ↔ LdBPK_201740.1 +4 more	OG7
LmjF.20.1570 ⚠ amidohydrolase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_201720.1 OG6 LdBPK_110640.1 ↔ LdBPK_201720.1 OG6 LdBPK_110630.1 ↔ LdBPK_201740.1 OG6 LdBPK_110640.1 ↔ LdBPK_201740.1 +9 more	Both
LmjF.34.2340 ⚠ asparaginyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG6 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 +1 more	Both
LmjF.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 OG7 LdBPK_110640.1 ↔ LdBPK_280470.1	OG7
LmjF.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_280470.1 OG7 LdBPK_110640.1 ↔ LdBPK_280470.1	OG7
LmjF.36.5620 ⚠ isoleucyl-tRNA synthetase, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 LdBPK_110630.1 ↔ LdBPK_365870.1 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_005560	Both
LmjF.30.0560 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG6 LdBPK_110640.1 ↔ LdBPK_300580.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003118 OG7 LdBPK_110640.1 ↔ LdBPK_300580.1	Both
LmjF.20.1185 ⚠ calpain-like cysteine peptidase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_007342 OG6 Tb927.11.6590 ↔ Tb927.9.7540	OG6
LmjF.35.0830 ⚠ NADH-dependent fumarate reductase-like protei	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LmjF.08.0410 ⚠ WD domain, G-beta repeat, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG6 LdBPK_080420.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_010560 OG7 LdBPK_080420.1 ↔ LdBPK_110640.1	Both
LmjF.36.4040 ⚠ hypothetical protein, conserved	—	OG6 LdBPK_110630.1 ↔ LdBPK_364240.1 OG6 LdBPK_110640.1 ↔ LdBPK_364240.1 OG7 TCSYLVIO_005560 ↔ TCSYLVIO_008197 OG7 LdBPK_110630.1 ↔ LdBPK_364240.1 +2 more	Both
LmjF.01.0610 ⚠ DNA-damage inducible protein DDI1-like protei	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003428 OG6 LdBPK_010630.1 ↔ LdBPK_110630.1 OG6 LdBPK_010630.1 ↔ LdBPK_110640.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003428 +3 more	Both
LmjF.21.0895 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	OG7
LmjF.20.1180 ⚠ calpain-like cysteine peptidase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_007342 OG6 Tb927.11.6590 ↔ Tb927.9.7540	OG6
LmjF.30.0760 ⚠ hypothetical protein, conserved	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_003145 OG6 LdBPK_110630.1 ↔ LdBPK_300810.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003145 OG7 LdBPK_110630.1 ↔ LdBPK_300810.1	Both
LmjF.35.1180 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LmjF.28.0330 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_110630.1 ↔ LdBPK_280470.1 OG6 LdBPK_110640.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_005560 OG7 LdBPK_280470.1 ↔ LdBPK_332700.1 +2 more	Both
LmjF.07.0800 ⚠ flavoprotein subunit-like protein	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LmjF.30.0460 ⚠ aspartyl-tRNA synthetase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_003867 OG7 LdBPK_110640.1 ↔ LdBPK_342110.1 OG7 TCSYLVIO_003107 ↔ TCSYLVIO_005560	OG7
LmjF.35.1190 ⚠ NADH-dependent fumarate reductase, putative	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_005159 OG6 TCSYLVIO_001670 ↔ TCSYLVIO_008502 OG6 LdBPK_110630.1 ↔ LdBPK_350850.1 OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005159 +2 more	Both
LmjF.04.0450 ⚠ cysteine peptidase, Clan CA, family C2, putat	—	OG6 TCSYLVIO_001670 ↔ TCSYLVIO_007342 OG6 Tb927.11.6590 ↔ Tb927.9.7540	OG6
LmjF.17.0620 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_110630.1 OG7 LdBPK_090800.1 ↔ LdBPK_332700.1 OG7 LdBPK_090800.1 ↔ LdBPK_110640.1	OG7
LmjF.30.0700 ⚠ nuclear movement protein, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_010327	OG7
LmjF.24.0820 ⚠ inositol polyphosphate phosphatase, putative	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_007569	OG7
LmjF.21.0540 ⚠ Lupus La protein homolog, putative	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_006827	OG7
LmjF.27.1340 ⚠ hypothetical protein, unknown function	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005512	OG7
LmjF.07.0760 ⚠ 6-phosphofructo-2-kinase/fructose-2,6-biphosp	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_002376	OG7
LmjF.35.3260 ⚠ Peroxin 19	—	OG7 TCSYLVIO_005560 ↔ TCSYLVIO_005818	OG7
LmjF.02.0140 ⚠ Ankyrin repeats (3 copies)/Zinc finger, C3HC4	—	OG6 LdBPK_020120.1 ↔ LdBPK_110640.1 OG7 LdBPK_020120.1 ↔ LdBPK_110640.1	Both
LmjF.03.0170 ⚠ hypothetical protein	—	OG6 LdBPK_030160.1 ↔ LdBPK_110630.1 OG6 LdBPK_030160.1 ↔ LdBPK_110640.1 OG7 LdBPK_030160.1 ↔ LdBPK_110630.1 OG7 LdBPK_030160.1 ↔ LdBPK_332700.1 +1 more	Both
LmjF.17.0082 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LmjF.34.2600 ⚠ acyl-CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_110630.1 OG7 LdBPK_090800.1 ↔ LdBPK_332700.1 OG7 LdBPK_090800.1 ↔ LdBPK_110640.1	OG7
LmjF.15.0040 ⚠ Possible lysine decarboxylase, putative	—	OG7 TCSYLVIO_002403 ↔ TCSYLVIO_005560	OG7
LmjF.17.0085 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LmjF.35.4150 ⚠ elongation factor 1-alpha, putative	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LmjF.36.4060 ⚠ regulator of chromosome condensation 1-like p	—	OG7 LdBPK_110630.1 ↔ LdBPK_260720.1 OG7 LdBPK_110640.1 ↔ LdBPK_260720.1 OG7 LdBPK_260720.1 ↔ LdBPK_332700.1	OG7
LmjF.30.3630 ⚠ CYC2-like protein, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_241960.1 OG7 LdBPK_110640.1 ↔ LdBPK_241960.1 OG7 LdBPK_241960.1 ↔ LdBPK_332700.1	OG7
LmjF.15.1300 ⚠ ubiquitin hydrolase, putative	—	OG7 LdBPK_332700.1 ↔ LdBPK_343890.1	OG7
LmjF.23.0300 ⚠ tryptophanyl-tRNA synthetase, putative	—	OG7 LdBPK_110630.1 ↔ LdBPK_290060.1 OG7 LdBPK_110640.1 ↔ LdBPK_290060.1 OG7 LdBPK_290060.1 ↔ LdBPK_332700.1	OG7
LmjF.06.0010 ⚠ histone H4	—	OG6 LdBPK_060010.1 ↔ LdBPK_110630.1 OG6 LdBPK_060010.1 ↔ LdBPK_110640.1 OG7 LdBPK_060010.1 ↔ LdBPK_110630.1 OG7 LdBPK_060010.1 ↔ LdBPK_332700.1 +1 more	Both
LmjF.36.2600 ⚠ cyclin-e binding protein 1-like protein	—	OG7 LdBPK_110630.1 ↔ LdBPK_260720.1 OG7 LdBPK_110640.1 ↔ LdBPK_260720.1 OG7 LdBPK_260720.1 ↔ LdBPK_332700.1	OG7
LmjF.04.0250 ⚠ RNA pseudouridylate synthase-like protein	—	OG7 LdBPK_110630.1 ↔ LdBPK_261140.1 OG7 LdBPK_110640.1 ↔ LdBPK_261140.1 OG7 LdBPK_261140.1 ↔ LdBPK_332700.1	OG7
LmjF.10.0890 ⚠ FKBP-type peptidyl-prolyl cis-trans isomerase	—	OG7 LdBPK_110630.1 ↔ LdBPK_291330.1 OG7 LdBPK_110640.1 ↔ LdBPK_291330.1 OG7 LdBPK_291330.1 ↔ LdBPK_332700.1	OG7
LmjF.17.0083 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LmjF.17.0081 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LmjF.17.0080 ⚠ elongation factor 1-alpha	—	OG7 LdBPK_111160.1 ↔ LdBPK_332700.1 OG7 LdBPK_110630.1 ↔ LdBPK_111160.1 OG7 LdBPK_110640.1 ↔ LdBPK_111160.1	OG7
LmjF.27.1270 ⚠ ubiquitin carboxyl-terminal hydrolase, putati	—	OG7 TCSYLVIO_001670 ↔ TCSYLVIO_005374	OG7

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