LmjF.01.0610

DNA-damage inducible protein DDI1-like protein
Leishmania major strain Friedlin OG6: OG6_101685 OG7: OG7_0006273 196 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 196 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.11.0620 ⚠
metallo-peptidase, Clan MF, Family M17
— +3 more Both
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— +3 more Both
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— +1 more Both
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.03.0800 ⚠
6-phosphofructo-2-kinase 1
— Both
LmjF.30.3630 ⚠
CYC2-like protein, putative
— OG7
LmjF.35.5210 ⚠
GTP-binding protein, putative
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.15.0360 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.24.2020
tubulin folding cofactor D, putative
— Both
LmjF.30.0560
hypothetical protein, conserved
— Both
LmjF.13.0940
N(2), N(2)-dimethylguanosine tRNA methyltrans
— Both
LmjF.22.0650
guide RNA associated protein, GAP2, putative
— Both
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— Both
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— Both
LmjF.30.1230
Zinc finger, C3HC4 type (RING finger), putati
— Both
LmjF.24.1900
WD domain, G-beta repeat/PFU (PLAA family ubi
— Both
LmjF.35.0900
hypothetical protein, conserved
— Both
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— Both
LmjF.34.1990
Zeta toxin, putative
— Both
LmjF.31.1370
hypothetical protein, conserved
— OG7
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmjF.33.1910
ribosome assembly protein RRB1, putative
— Both
LmjF.19.0260
C-terminal motor kinesin, putative
— OG6
LmjF.21.1430
2-oxoisovalerate dehydrogenase alpha subunit,
— Both
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— +2 more Both
LmjF.35.0700
vacuolar ATP synthase subunit d, putative
— Both
LmjF.36.6770 ⚠
beta adaptin, putative
— Both
LmjF.36.3100
ATP synthase, putative
— Both
LmjF.19.1040
phenylalanyl-tRNA synthetase, putative
— Both
LmjF.20.1180 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.35.3370
hypothetical protein, conserved
— Both
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— +2 more Both
LmjF.36.5420
branch point binding protein, putative
— Both
LmjF.08.0410
WD domain, G-beta repeat, putative
— Both
LmjF.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmjF.09.0740
ubiquitin ligase, putative
— Both
LmjF.18.0550
hypothetical protein, conserved
— Both
LmjF.34.4290
nucleolar protein family a, putative
— Both
LmjF.21.1340
ATP synthase, putative
— Both
LmjF.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.10.1200 ⚠
hypothetical protein, conserved
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.