LmjF.36.0150

6-phosphofructo-2-kinase/fructose-2,6-bisphosphatas, putative
Leishmania major strain Friedlin OG6: OG6_129420 OG7: OG7_0002306 141 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 141 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.2940 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— OG7
LmjF.33.0550 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0080 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.27.1620 ⚠
Eukaryotic translation initiation factor 4E-1
— OG7
LmjF.18.0350 ⚠
ATP12 chaperone protein, putative
— OG7
LmjF.14.1070 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.18.0070 ⚠
zinc-finger of a C2HC-type/Double zinc ribbon
— OG7
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— OG7
LmjF.29.0020 ⚠
transcription factor-like protein
— OG7
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmjF.32.0210 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.18.1320 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.0320 ⚠
TPR repeat, putative
— OG7
LmjF.05.0850 ⚠
zinc-finger of a C2HC-type, putative
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.34.2360 ⚠
hypothetical protein, conserved
— OG7
LmjF.14.0830 ⚠
CMGC/DYRK protein kinase, putative
— OG7
LmjF.25.2210 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1480 ⚠
eukaryotic translation initiation factor-like
— OG7
LmjF.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.27.1340 ⚠
hypothetical protein, unknown function
— OG7
LmjF.26.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2430 ⚠
Vacuolar proton pump subunit B, putative
— OG7
LmjF.21.0875 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— OG7
LmjF.36.3090 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0870 ⚠
phenylalanyl-tRNA synthetase alpha chain, put
— OG7
LmjF.36.3420 ⚠
vacuolar protein sorting-associated protein-l
— OG7
LmjF.04.0460 ⚠
adenylosuccinate lyase, putative
— OG7
LmjF.30.1550 ⚠
pseudouridine synthase A-like protein, putati
— OG7
LmjF.32.2730 ⚠
hypothetical protein, conserved
— OG7
LmjF.05.0150 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.0940 ⚠
oxidoreductase-like protein
— OG7
LmjF.30.2560 ⚠
hypothetical protein, conserved
— OG7
LmjF.04.0350 ⚠
hypothetical protein, conserved
— OG7
LmjF.06.0190 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4230 ⚠
paraflagellar rod component, putative
— OG7
LmjF.13.0210 ⚠
Triglyceride lipase, putative
— OG7
LmjF.26.0500 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.3220 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.1370 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2760 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— OG7
LmjF.34.3670 ⚠
vacuolar ATP synthase catalytic subunit A, pu
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.