LmjF.36.4230

paraflagellar rod component, putative
Leishmania major strain Friedlin OG6: OG6_110710 OG7: OG7_0002649 126 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 126 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.03.0800 ⚠
6-phosphofructo-2-kinase 1
— Both
LmjF.07.0760 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LmjF.35.2940 ⚠
Leucine carboxyl methyltransferase/Cupin-like
— Both
LmjF.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LmjF.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— Both
LmjF.09.0740
ubiquitin ligase, putative
— OG6
LmjF.32.0210
Histone chaperone Rttp106-like, putative
— OG6
LmjF.29.0320
TPR repeat, putative
— OG6
LmjF.18.1320
hypothetical protein, conserved
— OG6
LmjF.25.2210
hypothetical protein, conserved
— OG6
LmjF.04.0450 ⚠
cysteine peptidase, Clan CA, family C2, putat
— OG6
LmjF.05.0180
dihydrolipoamide branched chain transacylase,
— OG6
LmjF.32.2910
ubiquitin hydrolase, putative
— OG6
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG6
LmjF.18.1210 ⚠
prolyl-tRNA synthetase, putative
— OG6
LmjF.36.3090
hypothetical protein, conserved
— OG6
LmjF.18.1220 ⚠
bifunctional aminoacyl-tRNA synthetase, putat
— OG6
LmjF.23.0270
pteridine reductase 1
— OG6
LmjF.21.1770
ATP synthase F1 subunit gamma protein, putati
— OG6
LmjF.35.1410
threonyl-tRNA synthetase, putative
— OG6
LmjF.21.1650
protein kinase PK4, putative
— OG6
LmjF.10.0270
exonuclease, putative
— OG6
LmjF.25.2300
Leucine Rich repeats (2 copies), putative
— OG6
LmjF.20.0280
developmentally regulated phosphoprotein-like
— OG6
LmjF.33.1910
ribosome assembly protein RRB1, putative
— OG6
LmjF.19.0260
C-terminal motor kinesin, putative
— OG6
LmjF.21.1430
2-oxoisovalerate dehydrogenase alpha subunit,
— OG6
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— OG6
LmjF.35.0700
vacuolar ATP synthase subunit d, putative
— OG6
LmjF.36.3100
ATP synthase, putative
— OG6
LmjF.20.1180 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.34.1990
Zeta toxin, putative
— OG6
LmjF.21.1340
ATP synthase, putative
— OG6
LmjF.18.0550
hypothetical protein, conserved
— OG6
LmjF.23.0110
GDP-mannose pyrophosphorylase
— OG6
LmjF.30.0590 ⚠
Bardet-Biedl syndrome 2 protein
— OG7
LmjF.36.0080 ⚠
leucine carboxyl methyltransferase, putative
— OG7
LmjF.20.0930 ⚠
transmembrane protein, conserved
— OG7
LmjF.21.0330 ⚠
Vps51/Vps67, putative
— OG7
LmjF.32.3160 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LmjF.30.1450 ⚠
kinesin, putative
— OG7
LmjF.30.2390 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.3150 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.2630 ⚠
protein kinase, putative
— OG7
LmjF.30.3430 ⚠
protein mkt1, putative
— OG7
LmjF.12.1150 ⚠
hypothetical protein, unknown function
— OG7
LmjF.36.6030 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.2380 ⚠
hypothetical protein, unknown function
— OG7
LmjF.29.0710 ⚠
bardet-biedl syndrome 7 protein
— OG7
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.