LmjF.25.2300

Leucine Rich repeats (2 copies), putative
Leishmania major strain Friedlin OG6: OG6_119644 OG7: OG7_0017490 76 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
Applies on "Apply filters".
Reset
⬇ CSV
Network view all shared interactors, plus up to 150 more
Show:

Selection: Shift+drag also box-selects. Drag any selected node to move the whole selection.
Interactions 76 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.12.0250
cysteinyl-tRNA synthetase, putative
— Both
LmjF.03.0800 ⚠
6-phosphofructo-2-kinase 1
— OG7
LmjF.33.2570 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.36.4230
paraflagellar rod component, putative
— OG6
LmjF.35.0700
vacuolar ATP synthase subunit d, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— Both
LmjF.20.1185 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.08.0410
WD domain, G-beta repeat, putative
— Both
LmjF.36.0150 ⚠
6-phosphofructo-2-kinase/fructose-2,6-bisphos
— OG7
LmjF.09.0740
ubiquitin ligase, putative
— Both
LmjF.23.0110
GDP-mannose pyrophosphorylase
— Both
LmjF.34.1990
Zeta toxin, putative
— Both
LmjF.20.1180 ⚠
calpain-like cysteine peptidase, putative
— OG6
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— Both
LmjF.10.0270
exonuclease, putative
— Both
LmjF.35.1410
threonyl-tRNA synthetase, putative
— Both
LmjF.21.1770
ATP synthase F1 subunit gamma protein, putati
— Both
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
LmjF.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmjF.27.1340
hypothetical protein, unknown function
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.23.0270
pteridine reductase 1
— Both
LmjF.10.0160
hypothetical protein, conserved
— OG7
LmjF.15.1210 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LmjF.35.4230 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LmjF.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmjF.34.1220 ⚠
inositol 5-phosphatase-like protein
— OG7
LmjF.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.07.0760 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— OG7
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— Both
LmjF.35.3370
hypothetical protein, conserved
— Both
LmjF.18.0350
ATP12 chaperone protein, putative
— Both
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— Both
LmjF.30.0350
kinesin, putative
— OG6
LmjF.19.0260
C-terminal motor kinesin, putative
— OG6
LmjF.23.1165
coronin, putative
— Both
LmjF.34.2360
hypothetical protein, conserved
— Both
LmjF.19.1040
phenylalanyl-tRNA synthetase, putative
— Both
LmjF.32.0870
phenylalanyl-tRNA synthetase alpha chain, put
— Both
LmjF.26.0310 ⚠
6-phosphofructo-2-kinase/fructose-2,6-biphosp
— Both
LmjF.34.4090
GRIP domain containing protein, putative
— Both
Page 1 of 2
Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.