LmjF.12.0190

ubiquitin hydrolase, putative
Leishmania major strain Friedlin OG6: OG6_199649 OG7: OG7_0001214 210 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 210 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— Both
LmjF.18.0820 ⚠
hypothetical protein, conserved
— Both
LmjF.34.4090 ⚠
GRIP domain containing protein, putative
— Both
LmjF.23.0547 ⚠
hypothetical protein, conserved
— Both
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.26.0010 ⚠
brix domain containing-like protein
— OG7
LmjF.06.0830 ⚠
lipin, putative
— OG7
LmjF.20.1060 ⚠
hypothetical protein, unknown function
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.06.0540 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1230 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.1260 ⚠
mitochondrial DNA polymerase I protein A, put
— OG7
LmjF.24.0890 ⚠
DNA polymerase theta
— OG7
LmjF.28.0780 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LmjF.26.0390 ⚠
RET2, RNA editing complex MP57
— OG7
LmjF.19.1410 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmjF.14.0960 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LmjF.32.1680 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.03.0600 ⚠
arginine N-methyltransferase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.36.3090 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.27.1340 ⚠
hypothetical protein, unknown function
— OG7
LmjF.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.36.2420 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmjF.36.1150 ⚠
endonuclease/exonuclease/phosphatase, putativ
— OG7
LmjF.03.0120 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.35.4230 ⚠
synaptojanin (N-terminal domain), putative
— OG7
LmjF.15.1210 ⚠
inositol/phosphatidylinositol phosphatase, pu
— OG7
LmjF.10.0160 ⚠
hypothetical protein, conserved
— OG7
LmjF.08.0220 ⚠
ubiquitin-activating enzyme-like protein
— OG7
LmjF.35.3310 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LmjF.07.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.1700 ⚠
Leucine-rich repeat, putative
— OG7
LmjF.29.0020 ⚠
transcription factor-like protein
— OG7
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmjF.32.0210 ⚠
Histone chaperone Rttp106-like, putative
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.10.1200 ⚠
hypothetical protein, conserved
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.