LmjF.28.0780

kinetoplast poly(A) polymerase 1
Leishmania major strain Friedlin OG6: OG6_139718 OG7: OG7_0019075 118 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 118 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.14.1140 ⚠
hypothetical protein, conserved
— OG7
LmjF.02.0710 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.36.0190 ⚠
elongation factor 2
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— OG7
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmjF.36.0700 ⚠
MP18 RNA editing complex protein, putative
— OG7
LmjF.32.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmjF.07.0340 ⚠
ATP-dependent RNA helicase DBP2B, putative
— OG7
LmjF.35.3100 ⚠
ATP-dependent RNA helicase, putative
— OG7
LmjF.08.0080 ⚠
ATP-dependent DEAD/H RNA helicase, putative
— OG7
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— OG7
LmjF.36.2130 ⚠
ATP-dependent RNA helicase DBP2A, putative
— OG7
LmjF.28.2080 ⚠
DEAD-box ATP-dependent RNA helicase, mitochon
— OG7
LmjF.10.0140 ⚠
DEAD/DEAH box helicase, putative
— OG7
LmjF.21.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.1130 ⚠
intraflagellar transport protein 88, putative
— OG7
LmjF.36.6930 ⚠
RNA editing comple protein MP63
— OG7
LmjF.32.1680 ⚠
Paraflagellar Rod Proteome Component 9, putat
— OG7
LmjF.25.1720 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.0080 ⚠
hypothetical protein, conserved
— OG7
LmjF.18.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.20.1740 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.1730 ⚠
coatomer subunit epsilon
— OG7
LmjF.16.0080 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LmjF.28.1590 ⚠
Galactose oxidase, central domain containing
— OG7
LmjF.24.2090 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.36.6170 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.0210 ⚠
kelch domain-containing protein
— OG7
LmjF.24.0480 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.36.1470 ⚠
kelch motif containing protein, putative
— OG7
LmjF.22.1030 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.0560 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1760 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
LmjF.29.2360 ⚠
aspartyl aminopeptidase, putative
— OG7
LmjF.28.0940 ⚠
oxidoreductase-like protein
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.22.1230 ⚠
hypothetical protein, conserved
— OG7
LmjF.33.1970 ⚠
RNA editing complex protein MP46
— OG7
LmjF.19.0320 ⚠
intraflagellar transport protein 52
— OG7
LmjF.33.2260 ⚠
glycosyl hydrolase-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.