LmjF.25.1720

hypothetical protein, conserved
Leishmania major strain Friedlin OG6: OG6_200123 OG7: OG7_0044578 59 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 59 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.20.0260
Midasin, putative
— OG7
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— OG7
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmjF.32.0310
intraflagellar transport protein 140, putativ
— OG7
LmjF.27.1130
intraflagellar transport protein 88, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.14.0960 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.19.1410 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmjF.26.0390 ⚠
RET2, RNA editing complex MP57
— OG7
LmjF.23.0080
hypothetical protein, conserved
— OG7
LmjF.28.0780 ⚠
kinetoplast poly(A) polymerase 1
— OG7
LmjF.30.1090 ⚠
WW domain containing protein, putative
— OG7
LmjF.25.2080 ⚠
elongation factor 2-like protein
— OG7
LmjF.19.0320
intraflagellar transport protein 52
— OG7
LmjF.32.2980 ⚠
ATP binding protein-like protein
— OG7
LmjF.27.2200 ⚠
thioredoxin, putative
— OG7
LmjF.35.1760
proteasome complex subunit Rpn13 ubiquitin re
— OG7
LmjF.28.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1030 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1470 ⚠
kelch motif containing protein, putative
— OG7
LmjF.24.0480 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.20.0210 ⚠
kelch domain-containing protein
— OG7
LmjF.36.6170 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.2090 ⚠
Kelch motif/Galactose oxidase, central domain
— OG7
LmjF.28.1590 ⚠
Galactose oxidase, central domain containing
— OG7
LmjF.16.0080 ⚠
Galactose oxidase, central domain/Domain of u
— OG7
LmjF.32.1730
coatomer subunit epsilon
— OG7
LmjF.21.1020 ⚠
dynein arm light chain, putative
— OG7
LmjF.35.1650
hypothetical protein, conserved
— Both
LmjF.30.3090
RNA-binding protein 42 (RNA-binding motif pro
— Both
LmjF.35.3720
hypothetical protein, conserved
— OG7
LmjF.23.1220 ⚠
T-complex protein 1, gamma subunit, putative
— +4 more OG7
LmjF.21.1090 ⚠
T-complex protein 1, delta subunit, putative
— +4 more OG7
LmjF.32.1000 ⚠
chaperonin containing t-complex protein, puta
— +4 more OG7
LmjF.36.6910 ⚠
T-complex protein 1, theta subunit, putative
— +4 more OG7
LmjF.27.1260 ⚠
T-complex protein 1, beta subunit, putative
— +4 more OG7
LmjF.13.1660 ⚠
chaperonin TCP20, putative
— +4 more OG7
LmjF.35.3860 ⚠
T-complex protein 1, eta subunit, putative
— +4 more OG7
LmjF.32.3270 ⚠
chaperonin alpha subunit, putative
— +4 more OG7
LmjF.33.1080 ⚠
YEATS family, putative
— OG7
LmjF.26.1120 ⚠
axonemal dynein light chain, putative
— OG7
LmjF.24.0840 ⚠
dynein arm light chain, putative
— OG7
LmjF.06.0720 ⚠
YEATS family, putative
— Both
LmjF.33.1180 ⚠
Axonemal inner arm dynein light chain, putati
— OG7
LmjF.16.0290
proteasome 26S non-ATPase subunit 9, putative
— OG7
LmjF.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LmjF.21.1700 ⚠
proteasome alpha 2 subunit, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.