LmjF.20.0210

kelch domain-containing protein
Leishmania major strain Friedlin OG6: OG6_102848 OG7: OG7_0001012 153 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
Source datasets
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Interactions 153 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.02.0710 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmjF.29.1270 ⚠
Heat shock protein 100 kDa
— OG7
LmjF.27.2630 ⚠
ATP-dependent Clp protease subunit, heat shoc
— OG7
LmjF.36.3180 ⚠
receptor-type adenylate cyclase a-like protei
— OG7
LmjF.07.0270 ⚠
acetylornithine deacetylase-like protein
— OG7
LmjF.14.0910 ⚠
glutathione synthetase, putative
— OG7
LmjF.32.2980 ⚠
ATP binding protein-like protein
— OG7
LmjF.27.2200 ⚠
thioredoxin, putative
— OG7
LmjF.35.1760 ⚠
proteasome complex subunit Rpn13 ubiquitin re
— OG7
LmjF.14.0310 ⚠
proteasome alpha 3 subunit, putative
— OG7
LmjF.36.5240 ⚠
glycosyl hydrolase, putative
— OG7
LmjF.17.0235 ⚠
receptor-type adenylate cyclase b
— OG7
LmjF.18.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.14.0960 ⚠
RNA editing 3' terminal uridylyl transferase
— OG7
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— OG7
LmjF.26.1570 ⚠
thimet oligopeptidase, putative
— OG7
LmjF.36.6960 ⚠
elks delta-like protein
— OG7
LmjF.30.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.17.1390 ⚠
myo-inositol-1(or 4)-monophosphatase 1, putat
— OG7
LmjF.17.0237 ⚠
receptor-type adenylate cyclase b
— OG7
LmjF.30.0910 ⚠
ubiquitin-protein ligase, putative
— OG7
LmjF.32.2200 ⚠
U5 small nuclear ribonucleoprotein component,
— OG7
LmjF.30.3410 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.2240 ⚠
Glycosyl hydrolase family 65 central catalyti
— OG7
LmjF.21.1700 ⚠
proteasome alpha 2 subunit, putative
— OG7
LmjF.11.0240 ⚠
proteasome alpha 7 subunit, putative
— OG7
LmjF.16.1140 ⚠
WW domain containing protein, putative
— OG7
LmjF.35.5390 ⚠
HECT-domain (ubiquitin-transferase), putative
— OG7
LmjF.32.3870 ⚠
myosin XXI, putative
— OG7
LmjF.32.1730 ⚠
coatomer subunit epsilon
— OG7
LmjF.19.1410 ⚠
Cid1 family poly A polymerase, putative
— OG7
LmjF.11.0910 ⚠
Bromodomain factor 7, putative
— OG7
LmjF.20.1300 ⚠
small myristoylated protein-2
— OG7
LmjF.17.0230 ⚠
receptor-type adenylate cyclase b
— OG7
LmjF.21.1830 ⚠
proteasome subunit alpha type-5, putative
— OG7
LmjF.19.0320 ⚠
intraflagellar transport protein 52
— OG7
LmjF.02.0740 ⚠
dipeptylcarboxypeptidase, putative
— OG7
LmjF.12.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.1600 ⚠
proteasome subunit alpha type-1, putative
— OG7
LmjF.32.0310 ⚠
intraflagellar transport protein 140, putativ
— OG7
LmjF.36.0180 ⚠
elongation factor 2
— OG7
LmjF.33.2150 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.1530 ⚠
cell division cycle protein-like protein
— OG7
LmjF.15.1440 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LmjF.17.0200 ⚠
receptor-type adenylate cyclase a
— OG7
LmjF.35.3720 ⚠
hypothetical protein, conserved
— OG7
LmjF.20.0260 ⚠
Midasin, putative
— OG7
LmjF.25.1720 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.