LmjF.33.0310

ATP-binding cassette sub-family F member 1, putative
Leishmania major strain Friedlin OG6: OG6_104427 OG7: OG7_0001747 229 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 229 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.23.0547 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.1300 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.18.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.14.1360 ⚠
inositol-3-phosphate synthase
— Both
LmjF.12.0190 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.32.2910 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.27.1270 ⚠
ubiquitin carboxyl-terminal hydrolase, putati
— OG7
LmjF.35.2410 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.35.1740 ⚠
ubiquitin hydrolase, putative
— OG7
LmjF.18.1110 ⚠
Multisite-specific tRNA:(cytosine-C(5))-methy
— OG7
LmjF.34.3460 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.4090 ⚠
GRIP domain containing protein, putative
— OG7
LmjF.07.0280 ⚠
ubiquitin-protein ligase-like, putative
— OG7
LmjF.21.1330 ⚠
RecF/RecN/SMC N terminal domain/SMC proteins
— OG7
LmjF.18.0600 ⚠
Zn-finger in Ran binding protein and others/F
— OG7
LmjF.08.0510 ⚠
ribose-phosphate pyrophosphokinase, putative
— OG7
LmjF.31.2970 ⚠
acetyl-CoA carboxylase
— OG7
LmjF.35.3510 ⚠
structural maintenance of chromosome (SMC) fa
— OG7
LmjF.06.0950 ⚠
glucosamine-fructose-6-phosphate aminotransfe
— OG7
LmjF.05.0820 ⚠
hypothetical protein, conserved
— OG7
LmjF.29.2360 ⚠
aspartyl aminopeptidase, putative
— OG7
LmjF.35.0350 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.1240 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.24.1340 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.28.0940 ⚠
oxidoreductase-like protein
— OG7
LmjF.29.1580 ⚠
XPC-binding domain containing protein, putati
— OG7
LmjF.15.1440 ⚠
glutaminyl-tRNA synthetase, putative
— OG7
LmjF.29.2110 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— OG7
LmjF.30.3240 ⚠
glutamyl-tRNA synthetase, putative
— OG7
LmjF.26.0010 ⚠
brix domain containing-like protein
— OG7
LmjF.35.4550 ⚠
hypothetical protein, conserved
— OG7
LmjF.24.1170 ⚠
hypothetical protein, conserved
— OG7
LmjF.06.0830 ⚠
lipin, putative
— OG7
LmjF.22.0140 ⚠
hypothetical protein, conserved
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmjF.24.0750 ⚠
hypothetical protein, conserved
— OG7
LmjF.31.2980 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.27.0720 ⚠
UBA/TS-N domain containing protein, putative
— OG7
LmjF.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmjF.36.6070 ⚠
disgorgin, putative
— OG7
LmjF.30.1120 ⚠
importin alpha, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.30.2600 ⚠
formate--tetrahydrofolate ligase
— OG7
LmjF.18.0010 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
LmjF.36.2170 ⚠
NOL1/NOP2/sun family, putative
— OG7
LmjF.13.1100 ⚠
leucyl-tRNA synthetase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.