LmjF.36.6070

disgorgin, putative
Leishmania major strain Friedlin OG6: OG6_101755 OG7: OG7_0001257 145 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 145 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.32.2770 ⚠
mucin-like protein, putative
— OG7
LmjF.26.0140 ⚠
adenine phosphoribosyltransferase
— Both
LmjF.09.1140 ⚠
hypothetical protein, conserved
— Both
LmjF.30.3440 ⚠
DNA ligase I, putative
— Both
LmjF.30.3300 ⚠
UV excision repair RAD23-like protein
— Both
LmjF.06.0660 ⚠
hypothetical protein, conserved
— Both
LmjF.18.0010 ⚠
kinetoplast polyadenylation/uridylation facto
— Both
LmjF.22.1240 ⚠
translation initiation factor IF-2, putative
— Both
LmjF.29.2110 ⚠
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LmjF.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmjF.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmjF.36.7000 ⚠
PSP1 C-terminal conserved region, putative
— Both
LmjF.35.0950 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
LmjF.11.0140 ⚠
cell cycle sequence binding phosphoprotein (R
— Both
LmjF.05.0820 ⚠
hypothetical protein, conserved
— Both
LmjF.22.1540 ⚠
alanyl-tRNA synthetase, putative
— Both
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— Both
LmjF.35.1020 ⚠
hypothetical protein, unknown function
— Both
LmjF.31.1420 ⚠
hypothetical protein, conserved
— Both
LmjF.32.3980 ⚠
Gar1/Naf1 RNA binding region, putative
— Both
LmjF.23.1055 ⚠
HIT domain containing protein, putative
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.36.6160 ⚠
hypothetical protein, conserved
— Both
LmjF.26.1820 ⚠
hypothetical protein, conserved
— Both
LmjF.24.0500 ⚠
hypothetical protein, conserved
— Both
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.33.2960 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6020 ⚠
OTU-like cysteine protease, putative
— OG7
LmjF.13.0690 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.29.1120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.32.1550 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.10.0120 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.35.5000 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.36.4560 ⚠
PSP1 C-terminal conserved region, putative
— OG7
LmjF.27.1440 ⚠
Snf7, putative
— OG7
LmjF.35.3010 ⚠
trypanothione-dependent glyoxalase I
— OG7
LmjF.33.1400 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG7
LmjF.30.0700 ⚠
nuclear movement protein, putative
— OG7
LmjF.34.3430 ⚠
cleavage and polyadenylation specificity fact
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.1155 ⚠
Uncharacterised ACR, YggU family COG1872, put
— OG7
LmjF.35.2950 ⚠
pentatricopeptide repeat domain containing pr
— OG7
LmjF.29.1970 ⚠
hypothetical protein, unknown function
— OG7
LmjF.25.1580 ⚠
casein kinase I, putative
— OG7
LmjF.35.1000 ⚠
casein kinase I, putative
— OG7
LmjF.34.3020 ⚠
CK1/TTBK protein kinase, putative
— OG7
LmjF.04.1210 ⚠
casein kinase I, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.