LmjF.33.1400

STE/STE11 serine/threonine-protein kinase, putative
Leishmania major strain Friedlin OG6: OG6_479008 OG7: OG7_0005083 156 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 156 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.35.4550 ⚠
hypothetical protein, conserved
— Both
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.28.0330 ⚠
rrp44p homologue, putative
— Both
LmjF.14.1360 ⚠
inositol-3-phosphate synthase
— Both
LmjF.17.0350 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.20.1150 ⚠
Pre-mRNA-splicing factor 38, putative
— OG7
LmjF.30.0630 ⚠
histidyl-tRNA synthetase, putative
— OG7
LmjF.22.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.03.0060 ⚠
Met-10+ like-protein, putative
— OG7
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— OG7
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— OG7
LmjF.31.1130 ⚠
amidohydrolase, putative
— OG7
LmjF.31.2980 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.4100 ⚠
glycosyl hydrolase-like protein
— OG7
LmjF.18.0090 ⚠
alpha glucosidase II subunit, putative
— OG7
LmjF.21.0015 ⚠
histone H4
— OG7
LmjF.36.6080 ⚠
rab-like GTPase activating protein, putative
— OG7
LmjF.36.6070 ⚠
disgorgin, putative
— OG7
LmjF.30.1120 ⚠
importin alpha, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.30.2600 ⚠
formate--tetrahydrofolate ligase
— OG7
LmjF.18.0010 ⚠
kinetoplast polyadenylation/uridylation facto
— OG7
LmjF.22.0140 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.2950 ⚠
pentatricopeptide repeat domain containing pr
— OG7
LmjF.20.1710 ⚠
tRNA (Uracil-5-)-methyltransferase, putative
— OG7
LmjF.14.1320 ⚠
serine hydroxymethyltranferase (SHMT-S)
— OG7
LmjF.31.1930 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.28.2370 ⚠
serine hydroxymethyltransferase (SHMT-L)
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.36.0130 ⚠
PUB domain containing protein, putative
— OG7
LmjF.14.0450 ⚠
N-terminal conserved domain of Nudc./CS domai
— OG7
LmjF.34.1140 ⚠
dihydrouridine synthase (Dus), putative
— OG7
LmjF.25.2410 ⚠
hypothetical protein, conserved
— OG7
LmjF.23.0110 ⚠
GDP-mannose pyrophosphorylase
— OG7
LmjF.21.0810 ⚠
methionyl-tRNA synthetase
— OG7
LmjF.14.1370 ⚠
tyrosyl-tRNA synthetase, putative
— OG7
LmjF.22.0470 ⚠
Putative tRNA binding domain containing prote
— OG7
LmjF.16.1130 ⚠
tyrosyl or methionyl-tRNA synthetase-like pro
— OG7
LmjF.36.2420 ⚠
serine peptidase, Clan SC, Family S9B
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.22.1240 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.24.1340 ⚠
translation initiation factor IF-2, putative
— OG7
LmjF.22.0450 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LmjF.29.1580 ⚠
XPC-binding domain containing protein, putati
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.33.0770 ⚠
G1 cyclin CycE4, putative
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.