LmjF.14.1360

inositol-3-phosphate synthase

Leishmania major strain Friedlin OG6: OG6_100830 OG7: OG7_0006574 193 interactions (filtered)

Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used

Source datasets

T.brucei_2016_Gazestani

T.brucei_2017_Crozier

L.donovani_2025_Azimi

T.cruzi_2025_Azimi

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Network view up to 80 partners

Query Computational only Exp + computational Experimental only

Interactions 193 total

Partner	Experimental (Co-frac/MS)	Computational (OG inference)	OG
LmjF.04.0330 ⚠ mitochondrial exoribonuclease DSS-1, putative	—	OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	OG7
LmjF.11.1000 pyruvate phosphate dikinase, putative	—	OG6 LdBPK_111000.1 ↔ LdBPK_141450.1 OG6 Tb927.10.7110 ↔ Tb927.11.6280 OG7 Tb927.10.7110 ↔ Tb927.11.6280 OG7 LdBPK_111000.1 ↔ LdBPK_141450.1	Both
LmjF.33.0310 ⚠ ATP-binding cassette sub-family F member 1, p	—	OG6 LdBPK_141450.1 ↔ LdBPK_330340.1 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LmjF.19.0800 ⚠ ABC transport system ATP-binding protein, put	—	OG6 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	Both
LmjF.03.0160 ⚠ ATP-binding cassette protein subfamily F, mem	—	OG7 TCSYLVIO_006012 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_330340.1	OG7
LmjF.28.0450 ⚠ DIS3-like exonuclease, putative	—	OG6 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG6 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 +1 more	Both
LmjF.33.1400 ⚠ STE/STE11 serine/threonine-protein kinase, pu	—	OG6 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LmjF.23.0110 GDP-mannose pyrophosphorylase	—	OG6 TCSYLVIO_007453 ↔ TCSYLVIO_007603 OG6 Tb927.10.7110 ↔ Tb927.8.2050 OG7 Tb927.10.7110 ↔ Tb927.8.2050 OG7 TCSYLVIO_007453 ↔ TCSYLVIO_007603	Both
LmjF.25.0870 ⚠ Atypical serine/threonine protein kinase BUD3	—	OG6 TCSYLVIO_007401 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_331490.1 OG7 TCSYLVIO_007401 ↔ TCSYLVIO_007453	Both
LmjF.35.4550 hypothetical protein, conserved	—	OG6 TCSYLVIO_005710 ↔ TCSYLVIO_007453 OG6 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 LdBPK_141450.1 ↔ LdBPK_354620.1 OG7 TCSYLVIO_005710 ↔ TCSYLVIO_007453	Both
LmjF.28.0330 ⚠ rrp44p homologue, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_280470.1 OG7 TCSYLVIO_002525 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_002526 ↔ TCSYLVIO_007453 OG7 LdBPK_141450.1 ↔ LdBPK_280470.1	Both
LmjF.35.0750 proteasome activator protein pa26, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_350770.1 OG7 LdBPK_141450.1 ↔ LdBPK_350770.1	Both
LmjF.29.2060 ⚠ hypothetical protein, conserved	—	OG7 LdBPK_130530.1 ↔ LdBPK_141450.1	OG7
LmjF.12.0280 ornithine decarboxylase, putative	—	OG6 LdBPK_120105.1 ↔ LdBPK_141450.1 OG7 LdBPK_120105.1 ↔ LdBPK_141450.1	Both
LmjF.11.0210 ⚠ acidocalcisomal pyrophosphatase	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LmjF.03.0910 ⚠ inorganic pyrophosphatase, putative	—	OG6 TCSYLVIO_001709 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001709 ↔ TCSYLVIO_007453	Both
LmjF.32.3980 Gar1/Naf1 RNA binding region, putative	—	OG6 TCSYLVIO_000836 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_000836 ↔ TCSYLVIO_007453	Both
LmjF.36.5620 isoleucyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_004705 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004705 ↔ TCSYLVIO_007453	Both
LmjF.22.1540 alanyl-tRNA synthetase, putative	—	OG6 TCSYLVIO_001889 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001889 ↔ TCSYLVIO_007453	Both
LmjF.25.0170 ⚠ cleavage and polyadenylation specificity fact	—	OG6 TCSYLVIO_005414 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005414 ↔ TCSYLVIO_007453	Both
LmjF.05.0820 hypothetical protein, conserved	—	OG6 TCSYLVIO_001973 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001973 ↔ TCSYLVIO_007453	Both
LmjF.27.2390 ⚠ TPR-repeat protein, putative	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LmjF.36.0070 ⚠ stress-inducible protein STI1 homolog	—	OG6 TCSYLVIO_003496 ↔ TCSYLVIO_007453	OG6
LmjF.29.2110 UDP-glucose:glycoprotein glucosyltransferase,	—	OG6 TCSYLVIO_004363 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004363 ↔ TCSYLVIO_007453	Both
LmjF.36.2170 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LmjF.29.2540 ⚠ NOL1/NOP2/sun family, putative	—	OG6 TCSYLVIO_004998 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_004998 ↔ TCSYLVIO_007453	Both
LmjF.35.0390 hypothetical protein, conserved	—	OG6 TCSYLVIO_005084 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_005084 ↔ TCSYLVIO_007453	Both
LmjF.22.1240 ⚠ translation initiation factor IF-2, putative	—	OG6 TCSYLVIO_001768 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_001768 ↔ TCSYLVIO_007453	Both
LmjF.18.0090 ⚠ alpha glucosidase II subunit, putative	—	OG6 TCSYLVIO_006140 ↔ TCSYLVIO_007453 OG6 TCSYLVIO_006141 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006140 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006141 ↔ TCSYLVIO_007453	Both
LmjF.25.2120 eukaryotic translation initiation factor 3 su	—	OG6 TCSYLVIO_006404 ↔ TCSYLVIO_007453 OG7 TCSYLVIO_006404 ↔ TCSYLVIO_007453	Both
LmjF.34.1470 EAP30/Vps36 family, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_341570.1 OG7 LdBPK_141450.1 ↔ LdBPK_341570.1	Both
LmjF.23.1010 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_231180.1 OG7 LdBPK_141450.1 ↔ LdBPK_231180.1	Both
LmjF.30.1380 ⚠ amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LmjF.25.0410 translation initiation factor SUI1, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_250420.1 OG7 LdBPK_141450.1 ↔ LdBPK_250420.1	Both
LmjF.25.1030 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_251070.1 OG7 LdBPK_141450.1 ↔ LdBPK_251070.1	Both
LmjF.26.1160 ⚠ RNA pseudouridylate synthase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_261140.1 OG7 LdBPK_141450.1 ↔ LdBPK_261140.1	Both
LmjF.17.1410 zinc-finger protein ZPR1, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_171530.1 OG7 LdBPK_141450.1 ↔ LdBPK_171530.1	Both
LmjF.24.0140 ankyrin/TPR repeat protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_240130.1	OG6
LmjF.30.1540 phosphopantothenoylcysteine decarboxylase, pu	—	OG6 LdBPK_141450.1 ↔ LdBPK_301550.1 OG7 LdBPK_141450.1 ↔ LdBPK_301550.1	Both
LmjF.02.0710 ⚠ ATP-dependent Clp protease subunit, heat shoc	—	OG6 LdBPK_141450.1 ↔ LdBPK_291360.1 OG7 LdBPK_141450.1 ↔ LdBPK_291360.1	Both
LmjF.35.2270 ATP-dependent RNA helicase-like protein	—	OG6 LdBPK_141450.1 ↔ LdBPK_352320.1	OG6
LmjF.34.4060 ⚠ ubiquitin hydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_343890.1 OG7 LdBPK_141450.1 ↔ LdBPK_343890.1	Both
LmjF.30.2040 calpain-like cysteine peptidase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_302040.1	OG6
LmjF.24.1100 ⚠ pre-mRNA-splicing factor ATP-dependent RNA he	—	OG6 LdBPK_141450.1 ↔ LdBPK_241120.1	OG6
LmjF.15.0690 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_150720.1 OG7 LdBPK_141450.1 ↔ LdBPK_150720.1	Both
LmjF.17.0780 ⚠ Acyl CoA binding protein, putative	—	OG7 LdBPK_090800.1 ↔ LdBPK_141450.1	OG7
LmjF.29.2150 cdc2-related kinase 10, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_292260.1 OG7 LdBPK_141450.1 ↔ LdBPK_292260.1	Both
LmjF.31.1410 hypothetical protein, conserved	—	OG6 LdBPK_141450.1 ↔ LdBPK_311440.1 OG7 LdBPK_141450.1 ↔ LdBPK_311440.1	Both
LmjF.20.1570 ⚠ amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both
LmjF.20.1560 ⚠ amidohydrolase, putative	—	OG6 LdBPK_141450.1 ↔ LdBPK_201720.1 OG6 LdBPK_141450.1 ↔ LdBPK_201740.1 OG7 LdBPK_141450.1 ↔ LdBPK_201720.1 OG7 LdBPK_141450.1 ↔ LdBPK_201740.1	Both

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