LmjF.14.1360

inositol-3-phosphate synthase
Leishmania major strain Friedlin OG6: OG6_100830 OG7: OG7_0006574 193 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 193 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.11.1000
pyruvate phosphate dikinase, putative
— Both
LmjF.33.0310 ⚠
ATP-binding cassette sub-family F member 1, p
— Both
LmjF.19.0800 ⚠
ABC transport system ATP-binding protein, put
— Both
LmjF.03.0160 ⚠
ATP-binding cassette protein subfamily F, mem
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— +1 more Both
LmjF.33.1400 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— Both
LmjF.23.0110
GDP-mannose pyrophosphorylase
— Both
LmjF.25.0870 ⚠
Atypical serine/threonine protein kinase BUD3
— Both
LmjF.35.4550
hypothetical protein, conserved
— Both
LmjF.28.0330 ⚠
rrp44p homologue, putative
— Both
LmjF.35.0750
proteasome activator protein pa26, putative
— Both
LmjF.29.2060 ⚠
hypothetical protein, conserved
— OG7
LmjF.12.0280
ornithine decarboxylase, putative
— Both
LmjF.11.0210 ⚠
acidocalcisomal pyrophosphatase
— Both
LmjF.03.0910 ⚠
inorganic pyrophosphatase, putative
— Both
LmjF.32.3980
Gar1/Naf1 RNA binding region, putative
— Both
LmjF.36.5620
isoleucyl-tRNA synthetase, putative
— Both
LmjF.22.1540
alanyl-tRNA synthetase, putative
— Both
LmjF.25.0170 ⚠
cleavage and polyadenylation specificity fact
— Both
LmjF.05.0820
hypothetical protein, conserved
— Both
LmjF.27.2390 ⚠
TPR-repeat protein, putative
— OG6
LmjF.36.0070 ⚠
stress-inducible protein STI1 homolog
— OG6
LmjF.29.2110
UDP-glucose:glycoprotein glucosyltransferase,
— Both
LmjF.36.2170 ⚠
NOL1/NOP2/sun family, putative
— Both
LmjF.29.2540 ⚠
NOL1/NOP2/sun family, putative
— Both
LmjF.35.0390
hypothetical protein, conserved
— Both
LmjF.22.1240 ⚠
translation initiation factor IF-2, putative
— Both
LmjF.18.0090 ⚠
alpha glucosidase II subunit, putative
— Both
LmjF.25.2120
eukaryotic translation initiation factor 3 su
— Both
LmjF.34.1470
EAP30/Vps36 family, putative
— Both
LmjF.23.1010
hypothetical protein, conserved
— Both
LmjF.30.1380 ⚠
amidohydrolase, putative
— Both
LmjF.25.0410
translation initiation factor SUI1, putative
— Both
LmjF.25.1030
hypothetical protein, conserved
— Both
LmjF.26.1160 ⚠
RNA pseudouridylate synthase, putative
— Both
LmjF.17.1410
zinc-finger protein ZPR1, putative
— Both
LmjF.24.0140
ankyrin/TPR repeat protein
— OG6
LmjF.30.1540
phosphopantothenoylcysteine decarboxylase, pu
— Both
LmjF.02.0710 ⚠
ATP-dependent Clp protease subunit, heat shoc
— Both
LmjF.35.2270
ATP-dependent RNA helicase-like protein
— OG6
LmjF.34.4060 ⚠
ubiquitin hydrolase, putative
— Both
LmjF.30.2040
calpain-like cysteine peptidase, putative
— OG6
LmjF.24.1100 ⚠
pre-mRNA-splicing factor ATP-dependent RNA he
— OG6
LmjF.15.0690
hypothetical protein, conserved
— Both
LmjF.17.0780 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.29.2150
cdc2-related kinase 10, putative
— Both
LmjF.31.1410
hypothetical protein, conserved
— Both
LmjF.20.1570 ⚠
amidohydrolase, putative
— Both
LmjF.20.1560 ⚠
amidohydrolase, putative
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.