LmjF.11.1000

pyruvate phosphate dikinase, putative
Leishmania major strain Friedlin OG6: OG6_100727 OG7: OG7_0004964 148 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 148 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.14.1360
inositol-3-phosphate synthase
— Both
LmjF.36.0540 ⚠
ubiquitin-like protein, putative
— OG7
LmjF.01.0610
DNA-damage inducible protein DDI1-like protei
— Both
LmjF.15.1060 ⚠
tryparedoxin peroxidase
— Both
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— Both
LmjF.34.3670
vacuolar ATP synthase catalytic subunit A, pu
— Both
LmjF.15.1140 ⚠
tryparedoxin peroxidase
— Both
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmjF.15.1160 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1100 ⚠
tryparedoxin peroxidase
— Both
LmjF.26.0030
pyridoxal phosphate containing glycine decarb
— Both
LmjF.36.3100
ATP synthase, putative
— Both
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— Both
LmjF.36.3910
S-adenosylhomocysteine hydrolase
— Both
LmjF.15.1080 ⚠
tryparedoxin peroxidase
— Both
LmjF.15.1040 ⚠
tryparedoxin peroxidase
— Both
LmjF.06.0370
glutamine synthetase, putative
— Both
LmjF.23.0340
(H+)-ATPase G subunit, putative
— Both
LmjF.15.1120 ⚠
tryparedoxin peroxidase
— Both
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— Both
LmjF.23.0040 ⚠
peroxidoxin
— Both
LmjF.15.1010
glutamate dehydrogenase
— Both
LmjF.34.0080
glucose-6-phosphate 1-dehydrogenase, putative
— Both
LmjF.03.0200
delta-1-pyrroline-5-carboxylate dehydrogenase
— Both
LmjF.02.0310
Soluble NSF attachment protein, SNAP, putativ
— Both
LmjF.04.1220
hypothetical protein, conserved
— Both
LmjF.21.0250 ⚠
hexokinase, putative
— Both
LmjF.21.0240 ⚠
hexokinase, putative
— Both
LmjF.34.2600 ⚠
acyl-CoA binding protein, putative
— OG7
LmjF.17.0780 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.17.0620 ⚠
Acyl CoA binding protein, putative
— OG7
LmjF.15.0360 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.36.4060 ⚠
regulator of chromosome condensation 1-like p
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.17.0082 ⚠
elongation factor 1-alpha
— OG7
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.36.2600 ⚠
cyclin-e binding protein 1-like protein
— OG7
LmjF.11.0420 ⚠
regulator of chromatin condensation, putative
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.26.0740 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.17.0240 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.27.1690 ⚠
mRNA export factor MEX67
— OG7
LmjF.35.4150 ⚠
elongation factor 1-alpha, putative
— OG7
LmjF.29.2060 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.0083 ⚠
elongation factor 1-alpha
— OG7
LmjF.17.0081 ⚠
elongation factor 1-alpha
— OG7
LmjF.34.2020 ⚠
Regulator of chromosome condensation (RCC1) r
— OG7
LmjF.26.1370 ⚠
guanine nucleotide-binding protein-like prote
— OG7
LmjF.05.0460 ⚠
GTPase, putative
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.