LmjF.15.0360

RNA pseudouridylate synthase, putative
Leishmania major strain Friedlin OG6: OG6_129720 OG7: OG7_0001865 94 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 94 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.28.0450 ⚠
DIS3-like exonuclease, putative
— OG7
LmjF.31.1410 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.1150 ⚠
hypothetical protein, conserved
— OG7
LmjF.19.1530 ⚠
FK506-binding protein (FKBP)-type peptidyl-pr
— OG7
LmjF.35.4550 ⚠
hypothetical protein, conserved
— OG7
LmjF.28.0330 ⚠
rrp44p homologue, putative
— OG7
LmjF.19.0970 ⚠
peptidyl-prolyl cis-trans isomerase, macropha
— OG7
LmjF.22.1430 ⚠
fk506-binding protein 1-like protein
— OG7
LmjF.25.0870 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.34.1470 ⚠
EAP30/Vps36 family, putative
— OG7
LmjF.30.1540 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
LmjF.29.2150 ⚠
cdc2-related kinase 10, putative
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.19.0220 ⚠
polyprenyl synthase, putative
— OG7
LmjF.17.1410 ⚠
zinc-finger protein ZPR1, putative
— OG7
LmjF.15.0660 ⚠
hypothetical protein, conserved
— OG7
LmjF.25.0800 ⚠
DNL zinc finger, putative
— OG7
LmjF.36.6430 ⚠
protein transport protein Sec23-like protein
— OG7
LmjF.17.1310 ⚠
methyltransferase domain containing protein,
— OG7
LmjF.14.1360 ⚠
inositol-3-phosphate synthase
— OG7
LmjF.06.0010 ⚠
histone H4
— OG7
LmjF.21.0015 ⚠
histone H4
— OG7
LmjF.15.0010 ⚠
histone H4
— OG7
LmjF.27.1680 ⚠
hypothetical protein, conserved
— OG7
LmjF.06.0685 ⚠
hypothetical protein, conserved
— OG7
LmjF.26.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.0450 ⚠
Acetyltransferase (GNAT) family, putative
— OG7
LmjF.13.0260 ⚠
N-acetyltransferase subunit ARD1, putative
— OG7
LmjF.17.0940 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
LmjF.24.1890 ⚠
cyclin 10
— OG7
LmjF.24.1880 ⚠
cyclin 11, putative
— OG7
LmjF.33.0770 ⚠
G1 cyclin CycE4, putative
— OG7
LmjF.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.32.0820 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.30.3630 ⚠
CYC2-like protein, putative
— OG7
LmjF.36.0020 ⚠
histone H4
— OG7
LmjF.34.0310 ⚠
tRNA pseudouridine synthase, putative
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.30.0470 ⚠
hypothetical protein, conserved
— OG7
LmjF.36.6220 ⚠
flagellum transition zone component, putative
— OG7
LmjF.33.1400 ⚠
STE/STE11 serine/threonine-protein kinase, pu
— OG7
LmjF.19.1020 ⚠
tRNA pseudouridine synthase A-like protein
— OG7
LmjF.30.3070 ⚠
tRNA (Guanine-1)-methyltransferase, putative
— OG7
LmjF.27.1690 ⚠
mRNA export factor MEX67
— OG7
LmjF.04.0330 ⚠
mitochondrial exoribonuclease DSS-1, putative
— OG7
LmjF.26.0420 ⚠
pseudouridylate synthase-like protein
— OG7
LmjF.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— Both
LmjF.11.0630 ⚠
metallo-peptidase, Clan MF, Family M17
— OG7
LmjF.09.0750 ⚠
acyl-CoA binding protein, putative
— OG7
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Orthogroup expansion — connections between the query proteins
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How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.