LmjF.36.0230

peptidyl-prolyl cis-trans isomerase, putative
Leishmania major strain Friedlin OG6: OG6_109419 OG7: OG7_0001020 156 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 156 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.36.4040 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.0970 ⚠
E1-like ubiquitin-activating enzyme, putative
— OG7
LmjF.16.0030 ⚠
arginine N-methyltransferase, type I
— OG7
LmjF.12.1270 ⚠
arginine N-methyltransferase-like protein
— OG7
LmjF.03.0120 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.3310 ⚠
Leucine Rich repeats (2 copies), putative
— OG7
LmjF.07.0300 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.0170 ⚠
U2 small nuclear ribonucleoprotein 40K, putat
— OG7
LmjF.25.1700 ⚠
Leucine-rich repeat, putative
— OG7
LmjF.03.0600 ⚠
arginine N-methyltransferase, putative
— OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— OG7
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.18.1370 ⚠
heat shock protein 110, putative
— OG7
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmjF.22.0060 ⚠
transcription factor-like protein
— OG7
LmjF.29.0600 ⚠
hypothetical protein, conserved
— OG7
LmjF.06.0540 ⚠
hypothetical protein, conserved
— OG7
LmjF.15.0660 ⚠
hypothetical protein, conserved
— OG7
LmjF.17.1410 ⚠
zinc-finger protein ZPR1, putative
— OG7
LmjF.19.0220 ⚠
polyprenyl synthase, putative
— OG7
LmjF.18.0650 ⚠
PA26 p53-induced protein (sestrin), putative
— OG7
LmjF.15.0360 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.04.0250 ⚠
RNA pseudouridylate synthase-like protein
— OG7
LmjF.26.1160 ⚠
RNA pseudouridylate synthase, putative
— OG7
LmjF.30.3630 ⚠
CYC2-like protein, putative
— OG7
LmjF.36.2440 ⚠
hypothetical protein, conserved
— OG7
LmjF.30.1540 ⚠
phosphopantothenoylcysteine decarboxylase, pu
— OG7
LmjF.30.0760 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.3900 ⚠
Histidine kinase-, DNA gyrase B-, and HSP90-l
— OG7
LmjF.30.3620 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.34.1470 ⚠
EAP30/Vps36 family, putative
— OG7
LmjF.25.0870 ⚠
Atypical serine/threonine protein kinase BUD3
— OG7
LmjF.23.0120 ⚠
Concanavalin A-like lectin/glucanases superfa
— OG7
LmjF.32.0820 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.29.0060 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.05.0710 ⚠
CYC2-like cyclin, putative
— OG7
LmjF.33.0770 ⚠
G1 cyclin CycE4, putative
— OG7
LmjF.24.1880 ⚠
cyclin 11, putative
— OG7
LmjF.17.0940 ⚠
Phosphorylated CTD interacting factor 1 WW do
— OG7
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmjF.24.1890 ⚠
cyclin 10
— OG7
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmjF.23.0300 ⚠
tryptophanyl-tRNA synthetase, putative
— OG7
LmjF.13.0260 ⚠
N-acetyltransferase subunit ARD1, putative
— OG7
LmjF.17.1030 ⚠
hypothetical protein, conserved
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.