LmjF.34.3900

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase, putative
Leishmania major strain Friedlin OG6: OG6_146732 OG7: OG7_0002830 151 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 151 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.19.1040 ⚠
phenylalanyl-tRNA synthetase, putative
— OG7
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— OG7
LmjF.12.0250 ⚠
cysteinyl-tRNA synthetase, putative
— OG7
LmjF.29.2360 ⚠
aspartyl aminopeptidase, putative
— OG7
LmjF.20.0280 ⚠
developmentally regulated phosphoprotein-like
— OG7
LmjF.24.0010 ⚠
pyruvate dehydrogenase (lipoamide) kinase, pu
— OG7
LmjF.23.1630 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.35.2340 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.36.6350 ⚠
poly(A)-specific ribonuclease PARN, putative
— OG7
LmjF.21.0895 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.34.2340 ⚠
asparaginyl-tRNA synthetase, putative
— OG7
LmjF.30.0460 ⚠
aspartyl-tRNA synthetase, putative
— OG7
LmjF.12.1270 ⚠
arginine N-methyltransferase-like protein
— OG7
LmjF.12.0330 ⚠
hypothetical protein, unknown function
— OG7
LmjF.06.0830 ⚠
lipin, putative
— OG7
LmjF.01.0610 ⚠
DNA-damage inducible protein DDI1-like protei
— OG7
LmjF.35.1180 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.07.0800 ⚠
flavoprotein subunit-like protein
— OG7
LmjF.35.1190 ⚠
NADH-dependent fumarate reductase, putative
— OG7
LmjF.35.0830 ⚠
NADH-dependent fumarate reductase-like protei
— OG7
LmjF.26.1900 ⚠
hypothetical protein, conserved
— OG7
LmjF.16.1150 ⚠
hypothetical protein, conserved
— OG7
LmjF.10.1200 ⚠
hypothetical protein, conserved
— OG7
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— OG7
LmjF.23.0270 ⚠
pteridine reductase 1
— OG7
LmjF.21.1770 ⚠
ATP synthase F1 subunit gamma protein, putati
— OG7
LmjF.06.0870 ⚠
protein arginine n-methyltransferase 7
— OG7
LmjF.36.0710 ⚠
Protein C21orf2 homolog, putative
— OG7
LmjF.15.0280 ⚠
ribonucleoprotein p18, mitochondrial precurso
— OG7
LmjF.10.0890 ⚠
FKBP-type peptidyl-prolyl cis-trans isomerase
— OG7
LmjF.01.0710 ⚠
ubiquitin activating enzyme, putative
— OG7
LmjF.35.1410 ⚠
threonyl-tRNA synthetase, putative
— OG7
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— OG7
LmjF.34.4090 ⚠
GRIP domain containing protein, putative
— OG7
LmjF.10.0270 ⚠
exonuclease, putative
— OG7
LmjF.06.0540 ⚠
hypothetical protein, conserved
— OG7
LmjF.34.1220 ⚠
inositol 5-phosphatase-like protein
— OG7
LmjF.36.6770 ⚠
beta adaptin, putative
— OG7
LmjF.36.5260 ⚠
Adaptor protein complex AP-3 subunit beta-3
— OG7
LmjF.36.0230 ⚠
peptidyl-prolyl cis-trans isomerase, putative
— OG7
LmjF.28.0940 ⚠
oxidoreductase-like protein
— OG7
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— OG7
LmjF.34.1990 ⚠
Zeta toxin, putative
— OG7
LmjF.29.1240 ⚠
Hsp70 protein/TPR repeat, putative
— OG7
LmjF.05.0180 ⚠
dihydrolipoamide branched chain transacylase,
— OG7
LmjF.28.2770 ⚠
heat-shock protein hsp70, putative
— OG7
LmjF.24.0820 ⚠
inositol polyphosphate phosphatase, putative
— OG7
LmjF.01.0640 ⚠
HSP70-like protein
— OG7
LmjF.11.0990 ⚠
adaptin-related protein-like protein
— OG7
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.