LmjF.28.2770

heat-shock protein hsp70, putative
Leishmania major strain Friedlin OG6: OG6_100083 OG7: OG7_0000779 234 interactions (filtered)
Experimental Direct co-fractionation MS evidence Computational Inferred by orthology (OG) transfer ⚠ Ambiguous: multiple orthologs in target organism OG6 / OG7 Ortholog group version used
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Interactions 234 total
Partner Experimental (Co-frac/MS) Computational (OG inference) OG
LmjF.18.1370 ⚠
heat shock protein 110, putative
— +3 more Both
LmjF.28.1200 ⚠
luminal binding protein 1 (BiP), putative
— +7 more Both
LmjF.30.2550 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LmjF.30.2490 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LmjF.35.4710 ⚠
170 kDa glucose-regulated protein, putative
— +2 more OG7
LmjF.30.2480 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LmjF.26.0900 ⚠
heat shock 70 protein-like protein
— +2 more OG7
LmjF.18.0550 ⚠
hypothetical protein, conserved
— Both
LmjF.01.0640 ⚠
HSP70-like protein
— +2 more OG7
LmjF.30.2460 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LmjF.26.1240 ⚠
heat shock protein 70-related protein
— +7 more Both
LmjF.28.2780 ⚠
heat-shock protein hsp70, putative
— +7 more Both
LmjF.28.2820 ⚠
heat shock protein 70, putative
— +1 more OG6
LmjF.30.2470 ⚠
heat shock 70-related protein 1, mitochondria
— +8 more Both
LmjF.13.0260 ⚠
N-acetyltransferase subunit ARD1, putative
— OG7
LmjF.23.0820 ⚠
SET domain containing protein, putative
— OG7
LmjF.27.0160 ⚠
SET domain containing protein, putative
— OG7
LmjF.34.1050 ⚠
TPR repeat/SET domain containing protein, put
— OG7
LmjF.23.0790 ⚠
SET domain containing protein, putative
— OG7
LmjF.24.1750 ⚠
SET domain containing protein, putative
— OG7
LmjF.08.0550 ⚠
eukaryotic translation initiation factor 2 be
— OG7
LmjF.31.0160 ⚠
DNA-directed RNA polymerase II subunit 2, put
— OG7
LmjF.20.0010 ⚠
DNA-directed RNA polymerase III, putative
— OG7
LmjF.15.1220 ⚠
DnaJ domain/DnaJ central domain containing pr
— OG7
LmjF.25.1100 ⚠
DNAj-like protein
— OG7
LmjF.21.0490 ⚠
DnaJ protein, putative
— OG7
LmjF.19.1100 ⚠
hypothetical protein, conserved
— OG7
LmjF.27.2400 ⚠
heat shock protein DNAJ, putative
— OG7
LmjF.31.2130 ⚠
hypothetical protein, conserved
— OG7
LmjF.32.3300 ⚠
chaperone protein DnaJ, putative
— OG7
LmjF.33.0900 ⚠
dnaj chaperone-like protein
— OG7
LmjF.35.2980 ⚠
chaperone protein DnaJ, putative
— OG7
LmjF.04.0780 ⚠
heat shock protein, putative
— OG7
LmjF.36.2110 ⚠
chaperone protein DnaJ, putative
— OG7
LmjF.23.0310 ⚠
hypothetical protein, conserved
— OG7
LmjF.22.0080 ⚠
heat shock protein DNAJ, putative
— OG7
LmjF.29.1760 ⚠
paraflagellar rod protein 1D, putative
— OG7
LmjF.29.1770 ⚠
paraflagellar rod protein 1D, putative
— OG7
LmjF.22.0650 ⚠
guide RNA associated protein, GAP2, putative
— OG6
LmjF.36.0580 ⚠
hypothetical protein, unknown function
— OG7
LmjF.28.2740 ⚠
receptor for activated C kinase 1
— OG7
LmjF.28.2750 ⚠
receptor for activated C kinase 1
— OG7
LmjF.08.0410 ⚠
WD domain, G-beta repeat, putative
— OG7
LmjF.23.1770 ⚠
exosome component CSL4, putative
— Both
LmjF.24.2020 ⚠
tubulin folding cofactor D, putative
— OG6
LmjF.32.0400 ⚠
ATP-dependent RNA helicase HEL67
— Both
LmjF.36.2020 ⚠
chaperonin HSP60, mitochondrial precursor
— Both
LmjF.36.1430 ⚠
translation elongation factor 1-beta, putativ
— Both
LmjF.27.1870 ⚠
trypanothione synthetase
— Both
LmjF.34.0820 ⚠
elongation factor 1-beta
— Both
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Orthogroup expansion — connections between the query proteins
list 30/60/…
How many partner orthogroups appear in the table below. It does not change the analysis — the counts in the summary line always cover all partners.
degree ≤ N
Drops partners that interact with more than N orthogroups across the whole network. Promiscuous hubs connect to everything and explain nothing: the top partner of this query set by raw degree is a retrotransposon hot spot protein touching 586 orthogroups.
Score
(queries touched + 2 if bridge + 0.5 if other-network) ÷ log2(2 + degree). Rewards partners that connect the query set; penalises promiscuity.
Queries
How many of the query proteins' orthogroups this partner interacts with. 2 or more makes it a shared partner.
bridge
It links query proteins that came from different organisms.
other network
At least one of its links is supported only by a dataset from an organism other than that query protein's own — invisible in the network being searched. This is the discovery signal.
complex N
The partner belongs to conserved complex N (two or more datasets).
hub
Degree above 150 — interpret with care.
Click Analyse to look for partners that link the query proteins through the orthogroup network, including links only visible in another organism's dataset.